Surgical treatment of multiple deforming xanthomas of the foot and ankle with complete excision and rotational skin flaps: A case report
Xanthomas are cholesterol rich nodular dermal lesions characterized by lipid-laden macrophages that accumulate in skin and tendons.1 These lesions are frequently associated with hyperlipidemia disorders characterized by impaired cholesterol metabolism and accelerated atherosclerotic plaque developme...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-01-01
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| Series: | Foot & Ankle Surgery: Techniques, Reports & Cases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667396722000313 |
| _version_ | 1818214543787032576 |
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| author | Qanita Ali, DPM Rachelle Randall, DPM Lawrence M. Fallat, DPM, FACFAS |
| author_facet | Qanita Ali, DPM Rachelle Randall, DPM Lawrence M. Fallat, DPM, FACFAS |
| author_sort | Qanita Ali, DPM |
| collection | DOAJ |
| description | Xanthomas are cholesterol rich nodular dermal lesions characterized by lipid-laden macrophages that accumulate in skin and tendons.1 These lesions are frequently associated with hyperlipidemia disorders characterized by impaired cholesterol metabolism and accelerated atherosclerotic plaque development.2 Until recently, xanthomas were considered mere cosmetic lesions, however extensive evidence has shown that the presence of xanthomas signify increased cardiovascular risk and reduced average lifespan.3 Treatment centers around lipid lowering agents and rarely are these masses large enough to require surgical resection, thus there is very little literature discussing proper surgical excision.4, 5 We present a rare case of a 65 year old female with multiple painful deforming xanthoma masses large enough to cause an inability to fit into shoe gear, ambulate, or dorsiflex her ankle joints. Due to the size of these masses, excision of the lesions would result in large skin deficits and the presence of multiple wounds often requiring staged excisions with application of skin grafts and wound VACs. Our report demonstrates a rare and unusual case of large deforming xanthomas in the foot and ankle successfully treated with complete surgical excision during a single procedure. |
| first_indexed | 2024-12-12T06:21:52Z |
| format | Article |
| id | doaj.art-555d59dee3244e25aa0e8bfbde5b8ced |
| institution | Directory Open Access Journal |
| issn | 2667-3967 |
| language | English |
| last_indexed | 2024-12-12T06:21:52Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Foot & Ankle Surgery: Techniques, Reports & Cases |
| spelling | doaj.art-555d59dee3244e25aa0e8bfbde5b8ced2022-12-22T00:34:53ZengElsevierFoot & Ankle Surgery: Techniques, Reports & Cases2667-39672022-01-0122100173Surgical treatment of multiple deforming xanthomas of the foot and ankle with complete excision and rotational skin flaps: A case reportQanita Ali, DPM0Rachelle Randall, DPM1Lawrence M. Fallat, DPM, FACFAS2Corresponding author at: Beaumont Hospital Wayne, 33155 Annapolis St, Wayne, MI 48184, USA; Beaumont Health Wayne, Podiatric Foot and Ankle Surgical Residency, Beaumont Hospital Wayne, Wayne, MI 48184, USA.Beaumont Health Wayne, Podiatric Foot and Ankle Surgical Residency, Beaumont Hospital Wayne, Wayne, MI 48184, USA.Beaumont Health Wayne, Podiatric Foot and Ankle Surgical Residency, Beaumont Hospital Wayne, Wayne, MI 48184, USA.Xanthomas are cholesterol rich nodular dermal lesions characterized by lipid-laden macrophages that accumulate in skin and tendons.1 These lesions are frequently associated with hyperlipidemia disorders characterized by impaired cholesterol metabolism and accelerated atherosclerotic plaque development.2 Until recently, xanthomas were considered mere cosmetic lesions, however extensive evidence has shown that the presence of xanthomas signify increased cardiovascular risk and reduced average lifespan.3 Treatment centers around lipid lowering agents and rarely are these masses large enough to require surgical resection, thus there is very little literature discussing proper surgical excision.4, 5 We present a rare case of a 65 year old female with multiple painful deforming xanthoma masses large enough to cause an inability to fit into shoe gear, ambulate, or dorsiflex her ankle joints. Due to the size of these masses, excision of the lesions would result in large skin deficits and the presence of multiple wounds often requiring staged excisions with application of skin grafts and wound VACs. Our report demonstrates a rare and unusual case of large deforming xanthomas in the foot and ankle successfully treated with complete surgical excision during a single procedure.http://www.sciencedirect.com/science/article/pii/S26673967220003135 Classification Rearfoot and Ankle Reconstruction |
| spellingShingle | Qanita Ali, DPM Rachelle Randall, DPM Lawrence M. Fallat, DPM, FACFAS Surgical treatment of multiple deforming xanthomas of the foot and ankle with complete excision and rotational skin flaps: A case report Foot & Ankle Surgery: Techniques, Reports & Cases 5 Classification Rearfoot and Ankle Reconstruction |
| title | Surgical treatment of multiple deforming xanthomas of the foot and ankle with complete excision and rotational skin flaps: A case report |
| title_full | Surgical treatment of multiple deforming xanthomas of the foot and ankle with complete excision and rotational skin flaps: A case report |
| title_fullStr | Surgical treatment of multiple deforming xanthomas of the foot and ankle with complete excision and rotational skin flaps: A case report |
| title_full_unstemmed | Surgical treatment of multiple deforming xanthomas of the foot and ankle with complete excision and rotational skin flaps: A case report |
| title_short | Surgical treatment of multiple deforming xanthomas of the foot and ankle with complete excision and rotational skin flaps: A case report |
| title_sort | surgical treatment of multiple deforming xanthomas of the foot and ankle with complete excision and rotational skin flaps a case report |
| topic | 5 Classification Rearfoot and Ankle Reconstruction |
| url | http://www.sciencedirect.com/science/article/pii/S2667396722000313 |
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