Down-Regulation of miR-140 Induces EMT and Promotes Invasion by Targeting Slug in Esophageal Cancer

Down-Regulation of miR-140 Induces EMT and Promotes Invasion by Targeting Slug in Esophageal Cancer

Background/Aims: MicroRNAs (miRNAs) are reported to regulate cell invasion and functions by interfering with the translation of target mRNAs, but the role of miRNAs in esophageal cancer (EC) remains unclear. Methods: RT-PCR and Western blot were used to detect the expression of miRNAs and candidate...

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Bibliographic Details
Main Authors: Weiling Li, Guojun Jiang, Jianping Zhou, Hongmin Wang, Zegang Gong, Zheng Zhang, Ke Min, Hongdi Zhu, Yongfei Tan
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
miR-140
Slug
Invasion
Esophageal cancer
EMT
Online Access:http://www.karger.com/Article/FullText/366351

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