Infection spread simulation technology in a mixed state of multi variant viruses

ATLM (Apparent Time Lag Model) was extended to simulate the spread of infection in a mixed state of the variant virus and original wild type. It is applied to the 4th wave of infection spread in Tokyo, and (1) the 4th wave bottoms out near the end of the state of emergency, and the number of infecte...

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Main Authors: Makoto Koizumi, Motoaki Utamura, Seiichi Kirikami
Format: Article
Language:English
Published: AIMS Press 2022-01-01
Series:AIMS Public Health
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/publichealth.2022002?viewType=HTML
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author Makoto Koizumi
Motoaki Utamura
Seiichi Kirikami
author_facet Makoto Koizumi
Motoaki Utamura
Seiichi Kirikami
author_sort Makoto Koizumi
collection DOAJ
description ATLM (Apparent Time Lag Model) was extended to simulate the spread of infection in a mixed state of the variant virus and original wild type. It is applied to the 4th wave of infection spread in Tokyo, and (1) the 4th wave bottoms out near the end of the state of emergency, and the number of infected people increases again. (2) The rate of increase will be mainly by d strain (L452R) virus, while the increase by a strain (N501Y) virus will be suppressed. (3) It is anticipated that the infection will spread during the Olympic Games. (4) When variant viruses compete, the infection of highly infectious virus rises sharply while the infection by weakly infectious ones has converged. (5) It is effective as an infection control measure to find an infected person early and shorten the period from infection to quarantine by PCR test or antigen test as a measure other than the vaccine.
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spelling doaj.art-556787cf7729498eaca28fe2b8497c0d2022-12-22T02:51:38ZengAIMS PressAIMS Public Health2327-89942022-01-0191172510.3934/publichealth.2022002Infection spread simulation technology in a mixed state of multi variant virusesMakoto Koizumi0Motoaki Utamura1Seiichi Kirikami21. PhD, Former researcher of Hitachi Ltd., Hitachi City, Ibaraki Prefecture, Japan2. PhD, PE, Former professor, Tokyo Institute of Technology, Tokyo, Japan3. Scholar, Former engineer of Hitachi Ltd., Hitachi City, Ibaraki Prefecture, JapanATLM (Apparent Time Lag Model) was extended to simulate the spread of infection in a mixed state of the variant virus and original wild type. It is applied to the 4th wave of infection spread in Tokyo, and (1) the 4th wave bottoms out near the end of the state of emergency, and the number of infected people increases again. (2) The rate of increase will be mainly by d strain (L452R) virus, while the increase by a strain (N501Y) virus will be suppressed. (3) It is anticipated that the infection will spread during the Olympic Games. (4) When variant viruses compete, the infection of highly infectious virus rises sharply while the infection by weakly infectious ones has converged. (5) It is effective as an infection control measure to find an infected person early and shorten the period from infection to quarantine by PCR test or antigen test as a measure other than the vaccine.https://www.aimspress.com/article/doi/10.3934/publichealth.2022002?viewType=HTMLvariant coronaviruscovid-19epidemiological modelpredictionmulti-variant virusdelay differential equation
spellingShingle Makoto Koizumi
Motoaki Utamura
Seiichi Kirikami
Infection spread simulation technology in a mixed state of multi variant viruses
AIMS Public Health
variant coronavirus
covid-19
epidemiological model
prediction
multi-variant virus
delay differential equation
title Infection spread simulation technology in a mixed state of multi variant viruses
title_full Infection spread simulation technology in a mixed state of multi variant viruses
title_fullStr Infection spread simulation technology in a mixed state of multi variant viruses
title_full_unstemmed Infection spread simulation technology in a mixed state of multi variant viruses
title_short Infection spread simulation technology in a mixed state of multi variant viruses
title_sort infection spread simulation technology in a mixed state of multi variant viruses
topic variant coronavirus
covid-19
epidemiological model
prediction
multi-variant virus
delay differential equation
url https://www.aimspress.com/article/doi/10.3934/publichealth.2022002?viewType=HTML
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