Physical characterization and biological tests of bioactive titanium surfaces prepared by short-time micro-arc oxidation in green electrolyte
Titanium (Ti) and its alloys are the most used biomaterials in dental and orthopedic implant applications. However, despite the good performance of these materials, implants may fail; therefore, several surface modification methodologies have been developed to increase the bioactivity of the metal s...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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IOP Publishing
2022-01-01
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| Series: | Materials Research Express |
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| Online Access: | https://doi.org/10.1088/2053-1591/ac4d53 |
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| author | Karina M Zaniolo Sonia R Biaggio Joni A Cirelli Mariana A Cominotte Nerilso Bocchi Romeu C Rocha-Filho |
| author_facet | Karina M Zaniolo Sonia R Biaggio Joni A Cirelli Mariana A Cominotte Nerilso Bocchi Romeu C Rocha-Filho |
| author_sort | Karina M Zaniolo |
| collection | DOAJ |
| description | Titanium (Ti) and its alloys are the most used biomaterials in dental and orthopedic implant applications. However, despite the good performance of these materials, implants may fail; therefore, several surface modification methodologies have been developed to increase the bioactivity of the metal surface, accelerating the osseointegration process while promoting improved corrosion performance. In this work, the production of a TiO _2 coating on titanium through a short-time micro-arc oxidation (MAO) in a green electrolyte (obtained by a mixed solution of K _3 PO _4 and Ca(CH _3 COO) _2 .H _2 O) is proposed, aiming at obtaining a porous oxide layer with Ca and P incorporation through an environmentally friendly experimental condition. The morphology, chemical composition, crystalline structure, wettability, hardness and bioactivity of the modified Ti surfaces were characterized. The MAO process at 250 V for 1 min in the green electrolyte solution allowed the production of a highly porous oxide surface in the anatase crystalline phase, with effective Ca and P incorporation. Pre-osteoblastic cells were used in in-vitro assays to analyze viability, adhesion, proliferation and ability to perform extracellular matrix mineralization on the Ti surfaces (polished and MAO-treated Ti). The MAO-treated Ti surface exhibited better results in the bioactivity tests, presenting more calcium phosphate precipitates. This surface also presented higher hardness, lower hydrophilicity and better performance in biological tests than the polished surface. The here-reported MAO-treated Ti surface is promising for dental implants, especially in patients having poor bone quality that requires greater stimulation for osteogenesis. |
| first_indexed | 2024-03-12T15:41:06Z |
| format | Article |
| id | doaj.art-556b0705c8f54275a23f37c75c3dc878 |
| institution | Directory Open Access Journal |
| issn | 2053-1591 |
| language | English |
| last_indexed | 2024-03-12T15:41:06Z |
| publishDate | 2022-01-01 |
| publisher | IOP Publishing |
| record_format | Article |
| series | Materials Research Express |
| spelling | doaj.art-556b0705c8f54275a23f37c75c3dc8782023-08-09T15:58:04ZengIOP PublishingMaterials Research Express2053-15912022-01-019202540110.1088/2053-1591/ac4d53Physical characterization and biological tests of bioactive titanium surfaces prepared by short-time micro-arc oxidation in green electrolyteKarina M Zaniolo0Sonia R Biaggio1https://orcid.org/0000-0003-2127-859XJoni A Cirelli2https://orcid.org/0000-0002-7082-9290Mariana A Cominotte3Nerilso Bocchi4https://orcid.org/0000-0002-9170-9925Romeu C Rocha-Filho5https://orcid.org/0000-0003-4699-2423Departamento de Química, Universidade Federal de São Carlos (UFSCar) , São Carlos, SP, BrazilDepartamento de Química, Universidade Federal de São Carlos (UFSCar) , São Carlos, SP, BrazilDepartamento de Diagnóstico e Cirurgia, Faculdade de Odontologia, Universidade Estadual Paulista (Unesp) , Araraquara, SP, BrazilDepartamento de Diagnóstico e Cirurgia, Faculdade de Odontologia, Universidade Estadual Paulista (Unesp) , Araraquara, SP, BrazilDepartamento de Química, Universidade Federal de São Carlos (UFSCar) , São Carlos, SP, BrazilDepartamento de Química, Universidade Federal de São Carlos (UFSCar) , São Carlos, SP, BrazilTitanium (Ti) and its alloys are the most used biomaterials in dental and orthopedic implant applications. However, despite the good performance of these materials, implants may fail; therefore, several surface modification methodologies have been developed to increase the bioactivity of the metal surface, accelerating the osseointegration process while promoting improved corrosion performance. In this work, the production of a TiO _2 coating on titanium through a short-time micro-arc oxidation (MAO) in a green electrolyte (obtained by a mixed solution of K _3 PO _4 and Ca(CH _3 COO) _2 .H _2 O) is proposed, aiming at obtaining a porous oxide layer with Ca and P incorporation through an environmentally friendly experimental condition. The morphology, chemical composition, crystalline structure, wettability, hardness and bioactivity of the modified Ti surfaces were characterized. The MAO process at 250 V for 1 min in the green electrolyte solution allowed the production of a highly porous oxide surface in the anatase crystalline phase, with effective Ca and P incorporation. Pre-osteoblastic cells were used in in-vitro assays to analyze viability, adhesion, proliferation and ability to perform extracellular matrix mineralization on the Ti surfaces (polished and MAO-treated Ti). The MAO-treated Ti surface exhibited better results in the bioactivity tests, presenting more calcium phosphate precipitates. This surface also presented higher hardness, lower hydrophilicity and better performance in biological tests than the polished surface. The here-reported MAO-treated Ti surface is promising for dental implants, especially in patients having poor bone quality that requires greater stimulation for osteogenesis.https://doi.org/10.1088/2053-1591/ac4d53micro-arc oxidationtitanium oxide coatingbiological testsbiomaterialmodified titanium surface |
| spellingShingle | Karina M Zaniolo Sonia R Biaggio Joni A Cirelli Mariana A Cominotte Nerilso Bocchi Romeu C Rocha-Filho Physical characterization and biological tests of bioactive titanium surfaces prepared by short-time micro-arc oxidation in green electrolyte Materials Research Express micro-arc oxidation titanium oxide coating biological tests biomaterial modified titanium surface |
| title | Physical characterization and biological tests of bioactive titanium surfaces prepared by short-time micro-arc oxidation in green electrolyte |
| title_full | Physical characterization and biological tests of bioactive titanium surfaces prepared by short-time micro-arc oxidation in green electrolyte |
| title_fullStr | Physical characterization and biological tests of bioactive titanium surfaces prepared by short-time micro-arc oxidation in green electrolyte |
| title_full_unstemmed | Physical characterization and biological tests of bioactive titanium surfaces prepared by short-time micro-arc oxidation in green electrolyte |
| title_short | Physical characterization and biological tests of bioactive titanium surfaces prepared by short-time micro-arc oxidation in green electrolyte |
| title_sort | physical characterization and biological tests of bioactive titanium surfaces prepared by short time micro arc oxidation in green electrolyte |
| topic | micro-arc oxidation titanium oxide coating biological tests biomaterial modified titanium surface |
| url | https://doi.org/10.1088/2053-1591/ac4d53 |
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