Genome-wide epitope mapping across multiple host species reveals significant diversity in antibody responses to Coxiella burnetii vaccination and infection

Genome-wide epitope mapping across multiple host species reveals significant diversity in antibody responses to Coxiella burnetii vaccination and infection

Coxiella burnetii is an important zoonotic bacterial pathogen of global importance, causing the disease Q fever in a wide range of animal hosts. Ruminant livestock, in particular sheep and goats, are considered the main reservoir of human infection. Vaccination is a key control measure, and two comm...

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Bibliographic Details
Main Authors: Emil Bach, Stephen F. Fitzgerald, Sarah E. Williams-MacDonald, Mairi Mitchell, William T. Golde, David Longbottom, Alasdair J. Nisbet, Annemieke Dinkla, Eric Sullivan, Richard S. Pinapati, John C. Tan, Leo A. B. Joosten, Hendrik-Jan Roest, Thomas Østerbye, Ad P. Koets, Søren Buus, Tom N. McNeilly
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
Coxiella burnetii
Q fever
peptide microarray
B cell epitope mapping
vaccination
serodiagnostic
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1257722/full

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