Electrochemical Surface Treatment of a β-titanium Alloy to Realize an Antibacterial Property and Bioactivity
In this study, micro-arc oxidation (MAO) was performed on a β-type titanium alloy, namely, Ti-29Nb-13Ta-4.6Zr alloy (TNTZ), to improve not only its antibacterial property but also bioactivity in body fluids. The surface oxide layer formed on TNTZ by MAO treatment in a mixture of calcium glycerophosp...
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MDPI AG
2016-03-01
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| Online Access: | http://www.mdpi.com/2075-4701/6/4/76 |
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| author | Yusuke Tsutsumi Mitsuo Niinomi Masaaki Nakai Masaya Shimabukuro Maki Ashida Peng Chen Hisashi Doi Takao Hanawa |
| author_facet | Yusuke Tsutsumi Mitsuo Niinomi Masaaki Nakai Masaya Shimabukuro Maki Ashida Peng Chen Hisashi Doi Takao Hanawa |
| author_sort | Yusuke Tsutsumi |
| collection | DOAJ |
| description | In this study, micro-arc oxidation (MAO) was performed on a β-type titanium alloy, namely, Ti-29Nb-13Ta-4.6Zr alloy (TNTZ), to improve not only its antibacterial property but also bioactivity in body fluids. The surface oxide layer formed on TNTZ by MAO treatment in a mixture of calcium glycerophosphate, calcium acetate, and silver nitrate was characterized using surface analyses. The resulting porous oxide layer was mainly composed of titanium oxide, and it also contained calcium, phosphorus, and a small amount of silver, all of which were incorporated from the electrolyte during the treatment. The MAO-treated TNTZ showed a strong inhibition effect on anaerobic Gram-negative bacteria when the electrolyte contained more than 0.5 mM silver ions. The formation of calcium phosphate on the surface of the specimens after immersion in Hanks’ solution was evaluated to determine the bioactivity of TNTZ with sufficient antibacterial property. As a result, thick calcium phosphate layers formed on the TNTZ specimen that underwent MAO treatment, whereas no precipitate was observed on TNTZ without treatment. Thus, the MAO treatment of titanium-based alloys is confirmed to be effective in realizing both antibacterial and bioactive properties. |
| first_indexed | 2024-04-13T19:10:11Z |
| format | Article |
| id | doaj.art-55705b383ad64a3682938b58c62ba261 |
| institution | Directory Open Access Journal |
| issn | 2075-4701 |
| language | English |
| last_indexed | 2024-04-13T19:10:11Z |
| publishDate | 2016-03-01 |
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| spelling | doaj.art-55705b383ad64a3682938b58c62ba2612022-12-22T02:33:51ZengMDPI AGMetals2075-47012016-03-01647610.3390/met6040076met6040076Electrochemical Surface Treatment of a β-titanium Alloy to Realize an Antibacterial Property and BioactivityYusuke Tsutsumi0Mitsuo Niinomi1Masaaki Nakai2Masaya Shimabukuro3Maki Ashida4Peng Chen5Hisashi Doi6Takao Hanawa7Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Chiyoda, Tokyo 101-0062, JapanInstitute for Materials Research, Tohoku University, Sendai, Miyagi 980-8577, JapanInstitute for Materials Research, Tohoku University, Sendai, Miyagi 980-8577, JapanGraduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Bunkyo, Tokyo 113-0034, JapanInstitute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Chiyoda, Tokyo 101-0062, JapanInstitute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Chiyoda, Tokyo 101-0062, JapanInstitute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Chiyoda, Tokyo 101-0062, JapanInstitute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Chiyoda, Tokyo 101-0062, JapanIn this study, micro-arc oxidation (MAO) was performed on a β-type titanium alloy, namely, Ti-29Nb-13Ta-4.6Zr alloy (TNTZ), to improve not only its antibacterial property but also bioactivity in body fluids. The surface oxide layer formed on TNTZ by MAO treatment in a mixture of calcium glycerophosphate, calcium acetate, and silver nitrate was characterized using surface analyses. The resulting porous oxide layer was mainly composed of titanium oxide, and it also contained calcium, phosphorus, and a small amount of silver, all of which were incorporated from the electrolyte during the treatment. The MAO-treated TNTZ showed a strong inhibition effect on anaerobic Gram-negative bacteria when the electrolyte contained more than 0.5 mM silver ions. The formation of calcium phosphate on the surface of the specimens after immersion in Hanks’ solution was evaluated to determine the bioactivity of TNTZ with sufficient antibacterial property. As a result, thick calcium phosphate layers formed on the TNTZ specimen that underwent MAO treatment, whereas no precipitate was observed on TNTZ without treatment. Thus, the MAO treatment of titanium-based alloys is confirmed to be effective in realizing both antibacterial and bioactive properties.http://www.mdpi.com/2075-4701/6/4/76titanium alloymicro-arc oxidationantibacterial propertybioactivityhard-tissue compatibility |
| spellingShingle | Yusuke Tsutsumi Mitsuo Niinomi Masaaki Nakai Masaya Shimabukuro Maki Ashida Peng Chen Hisashi Doi Takao Hanawa Electrochemical Surface Treatment of a β-titanium Alloy to Realize an Antibacterial Property and Bioactivity Metals titanium alloy micro-arc oxidation antibacterial property bioactivity hard-tissue compatibility |
| title | Electrochemical Surface Treatment of a β-titanium Alloy to Realize an Antibacterial Property and Bioactivity |
| title_full | Electrochemical Surface Treatment of a β-titanium Alloy to Realize an Antibacterial Property and Bioactivity |
| title_fullStr | Electrochemical Surface Treatment of a β-titanium Alloy to Realize an Antibacterial Property and Bioactivity |
| title_full_unstemmed | Electrochemical Surface Treatment of a β-titanium Alloy to Realize an Antibacterial Property and Bioactivity |
| title_short | Electrochemical Surface Treatment of a β-titanium Alloy to Realize an Antibacterial Property and Bioactivity |
| title_sort | electrochemical surface treatment of a β titanium alloy to realize an antibacterial property and bioactivity |
| topic | titanium alloy micro-arc oxidation antibacterial property bioactivity hard-tissue compatibility |
| url | http://www.mdpi.com/2075-4701/6/4/76 |
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