Antibiofilm Activity of Biocide Metal Ions Containing Bioactive Glasses (BGs): A Mini Review

One of the major clinical issues during the implantation procedure is the bacterial infections linked to biofilms. Due to their tissue localization and the type of bacteria involved, bacterial infections at implant sites are usually difficult to treat, which increases patient morbidity and even mort...

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Main Author: Irina Atkinson
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/9/10/489
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author Irina Atkinson
author_facet Irina Atkinson
author_sort Irina Atkinson
collection DOAJ
description One of the major clinical issues during the implantation procedure is the bacterial infections linked to biofilms. Due to their tissue localization and the type of bacteria involved, bacterial infections at implant sites are usually difficult to treat, which increases patient morbidity and even mortality. The difficulty of treating biofilm-associated infections and the emergence of multidrug-resistant bacteria are further challenges for the scientific community to develop novel biomaterials with excellent biocompatibility and antibacterial properties. Given their ability to stimulate bone formation and have antibacterial properties, metal ion-doped bioactive glasses (BGs) have received considerable research. This mini review aims to be successful in presenting the developments made about the role of biocide metal ions incorporated into BGs against the development of bacterial biofilms and the spread of nosocomial diseases.
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spelling doaj.art-5570e27e5dd74ef68b3af44a380895212023-11-23T22:56:47ZengMDPI AGBioengineering2306-53542022-09-0191048910.3390/bioengineering9100489Antibiofilm Activity of Biocide Metal Ions Containing Bioactive Glasses (BGs): A Mini ReviewIrina Atkinson0“Ilie Murgulescu” Institute of Physical Chemistry of the Romanian Academy, 202, Spl. Independentei, 060021 Bucharest, RomaniaOne of the major clinical issues during the implantation procedure is the bacterial infections linked to biofilms. Due to their tissue localization and the type of bacteria involved, bacterial infections at implant sites are usually difficult to treat, which increases patient morbidity and even mortality. The difficulty of treating biofilm-associated infections and the emergence of multidrug-resistant bacteria are further challenges for the scientific community to develop novel biomaterials with excellent biocompatibility and antibacterial properties. Given their ability to stimulate bone formation and have antibacterial properties, metal ion-doped bioactive glasses (BGs) have received considerable research. This mini review aims to be successful in presenting the developments made about the role of biocide metal ions incorporated into BGs against the development of bacterial biofilms and the spread of nosocomial diseases.https://www.mdpi.com/2306-5354/9/10/489bacterial biofilmbioactive glassmetal ions
spellingShingle Irina Atkinson
Antibiofilm Activity of Biocide Metal Ions Containing Bioactive Glasses (BGs): A Mini Review
Bioengineering
bacterial biofilm
bioactive glass
metal ions
title Antibiofilm Activity of Biocide Metal Ions Containing Bioactive Glasses (BGs): A Mini Review
title_full Antibiofilm Activity of Biocide Metal Ions Containing Bioactive Glasses (BGs): A Mini Review
title_fullStr Antibiofilm Activity of Biocide Metal Ions Containing Bioactive Glasses (BGs): A Mini Review
title_full_unstemmed Antibiofilm Activity of Biocide Metal Ions Containing Bioactive Glasses (BGs): A Mini Review
title_short Antibiofilm Activity of Biocide Metal Ions Containing Bioactive Glasses (BGs): A Mini Review
title_sort antibiofilm activity of biocide metal ions containing bioactive glasses bgs a mini review
topic bacterial biofilm
bioactive glass
metal ions
url https://www.mdpi.com/2306-5354/9/10/489
work_keys_str_mv AT irinaatkinson antibiofilmactivityofbiocidemetalionscontainingbioactiveglassesbgsaminireview