Atopic dermatitis - itchy problem of children and adults
Atopic dermatitis is a chronic inflammatory disease with recurrent exacerbations, persistent itching, erythema, dry skin due to damage to the epidermal barrier, and staphylococcal infections. The causative factors are mutations in the gene encoding filaggrin, dysregulation of the immune system, cha...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2024-02-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/48165 |
| _version_ | 1797303514332921856 |
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| author | Nina Lasota Gabriela Demidowicz Natalia Trąbka Patryk Lasek Maciej Smerdzyński Katarzyna Łach Kinga Ściurka Klaudia Kowalczyk Kinga Panuciak Karolina Kozicka |
| author_facet | Nina Lasota Gabriela Demidowicz Natalia Trąbka Patryk Lasek Maciej Smerdzyński Katarzyna Łach Kinga Ściurka Klaudia Kowalczyk Kinga Panuciak Karolina Kozicka |
| author_sort | Nina Lasota |
| collection | DOAJ |
| description |
Atopic dermatitis is a chronic inflammatory disease with recurrent exacerbations, persistent itching, erythema, dry skin due to damage to the epidermal barrier, and staphylococcal infections. The causative factors are mutations in the gene encoding filaggrin, dysregulation of the immune system, changes in the skin microbiome and lipids in the stratum corneum and deficiency of antimicrobial peptides AMPs. The disease mainly affects children, causing a significant deterioration in the quality of life, and its first symptoms occur in approximately 90% before the age of 5. Lesions most often appear on the bends of elbows and knees, on the face and neck, but may also affect the skin of the entire body (erythroderma). The location of the eruptions depends on age. Atopic dermatitis is the result of complex genetic, epigenetic, environmental and immunological interactions with a coexisting epidermal barrier defect. The disease is diagnosed based on the Hanifin and Rajka criteria. Treatment of atopic dermatitis is symptomatic and selected individually. They include the elimination of provoking factors, care of the epidermal barrier, and anti-inflammatory and anti-pruritic therapy.
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| first_indexed | 2024-03-07T23:54:51Z |
| format | Article |
| id | doaj.art-557725fbbacd400a9ede2b7e008e08ff |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-03-07T23:54:51Z |
| publishDate | 2024-02-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-557725fbbacd400a9ede2b7e008e08ff2024-02-18T11:53:02ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062024-02-015910.12775/JEHS.2024.59.004Atopic dermatitis - itchy problem of children and adultsNina Lasota0Gabriela Demidowicz1Natalia Trąbka2Patryk Lasek3Maciej Smerdzyński4Katarzyna Łach5Kinga Ściurka6Klaudia Kowalczyk7Kinga Panuciak8Karolina Kozicka9Private Health Center “Medicus”, Dmowskiego 37, 97-300 Piotrków TrybunalskiJoanna Bartoszewska M.D. 21-143 Abramów, Szkolna 10, Poland Medical Center ANAMED 21-100 Lubartów, Kolejowa 5, PolandDoctoral School, Medical University of Lublin, 7 Chodźki St., 20-093 Lublin, PolandCounty Health Center in Brzeziny sp. z o. o. st. Marii Skłodowskiej-Curie 6, 95-006 BrzezinyNon-public Health Care “Vivamed”, 24-300 Opole Lubelskie, Partyzancka 17a, PolandUniversity Hospital in Krakow 31-501 Kraków, Mikołaja Kopernika 36, PolandPharmacy “Centrum Zdrowia” Bankowa 5/u1, 72-010 PoliceIndependent Public Clinical Hospital No. 4 in Lublin Jaczewskiego 8, 20-954 LublinIndependent Public Clinical Hospital No. 4 in Lublin Jaczewskiego 8, 20-954 Lublin Atopic dermatitis is a chronic inflammatory disease with recurrent exacerbations, persistent itching, erythema, dry skin due to damage to the epidermal barrier, and staphylococcal infections. The causative factors are mutations in the gene encoding filaggrin, dysregulation of the immune system, changes in the skin microbiome and lipids in the stratum corneum and deficiency of antimicrobial peptides AMPs. The disease mainly affects children, causing a significant deterioration in the quality of life, and its first symptoms occur in approximately 90% before the age of 5. Lesions most often appear on the bends of elbows and knees, on the face and neck, but may also affect the skin of the entire body (erythroderma). The location of the eruptions depends on age. Atopic dermatitis is the result of complex genetic, epigenetic, environmental and immunological interactions with a coexisting epidermal barrier defect. The disease is diagnosed based on the Hanifin and Rajka criteria. Treatment of atopic dermatitis is symptomatic and selected individually. They include the elimination of provoking factors, care of the epidermal barrier, and anti-inflammatory and anti-pruritic therapy. https://apcz.umk.pl/JEHS/article/view/48165atopic dermatitisskin itchingemollientsglucocorticosteroidsHanifin and Rajka criteria |
| spellingShingle | Nina Lasota Gabriela Demidowicz Natalia Trąbka Patryk Lasek Maciej Smerdzyński Katarzyna Łach Kinga Ściurka Klaudia Kowalczyk Kinga Panuciak Karolina Kozicka Atopic dermatitis - itchy problem of children and adults Journal of Education, Health and Sport atopic dermatitis skin itching emollients glucocorticosteroids Hanifin and Rajka criteria |
| title | Atopic dermatitis - itchy problem of children and adults |
| title_full | Atopic dermatitis - itchy problem of children and adults |
| title_fullStr | Atopic dermatitis - itchy problem of children and adults |
| title_full_unstemmed | Atopic dermatitis - itchy problem of children and adults |
| title_short | Atopic dermatitis - itchy problem of children and adults |
| title_sort | atopic dermatitis itchy problem of children and adults |
| topic | atopic dermatitis skin itching emollients glucocorticosteroids Hanifin and Rajka criteria |
| url | https://apcz.umk.pl/JEHS/article/view/48165 |
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