Phytoconstituents as novel osteo-protective agents: Implications in bone health
Osteoporosis is a progressive and chronic bone disorder characterized by low bone mass and microarchitectural deterioration of skeletal tissues. Osteoporosis leads to alteration in bone mineral content resulting in decreased bone strength with elevated fracture risks frequently associated with great...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
IMR Press
2020-03-01
|
| Series: | Frontiers in Bioscience-Landmark |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/FBL/25/7/10.2741/4855 |
| _version_ | 1818207239297564672 |
|---|---|
| author | Zaffar Azam Vikas Pandey Navita Gupta Leena Sapra Hamid Y. Dar Niti Shokeen Asha Bhardwaj Ayaan Ahmad Vandana Soni Rupesh K. Srivastava |
| author_facet | Zaffar Azam Vikas Pandey Navita Gupta Leena Sapra Hamid Y. Dar Niti Shokeen Asha Bhardwaj Ayaan Ahmad Vandana Soni Rupesh K. Srivastava |
| author_sort | Zaffar Azam |
| collection | DOAJ |
| description | Osteoporosis is a progressive and chronic bone disorder characterized by low bone mass and microarchitectural deterioration of skeletal tissues. Osteoporosis leads to alteration in bone mineral content resulting in decreased bone strength with elevated fracture risks frequently associated with greater morbidity. The latest research in the area of photomedicine had sparked interest in harnessing the active components from plants in both disease control and management across the globe. We in the present review have taken a comprehensive approach to identify forty known plants and their phytoconstituents, which encompasses (i) the genetic diversity of various plants, (ii) their active components and (iii) their osteoprotective role in osteoporosis. Thus, the present review is an attempt for the first time to collectively document the therapeutic properties of valuable medicinal plants in preventing and treating bone loss in osteoporosis. |
| first_indexed | 2024-12-12T04:25:46Z |
| format | Article |
| id | doaj.art-55780908c2a5495fa823ed596672a726 |
| institution | Directory Open Access Journal |
| issn | 2768-6701 |
| language | English |
| last_indexed | 2024-12-12T04:25:46Z |
| publishDate | 2020-03-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Frontiers in Bioscience-Landmark |
| spelling | doaj.art-55780908c2a5495fa823ed596672a7262022-12-22T00:38:12ZengIMR PressFrontiers in Bioscience-Landmark2768-67012020-03-012571259129610.2741/4855S2768-6701(21)00106-4Phytoconstituents as novel osteo-protective agents: Implications in bone healthZaffar Azam0Vikas Pandey1Navita Gupta2Leena Sapra3Hamid Y. Dar4Niti Shokeen5Asha Bhardwaj6Ayaan Ahmad7Vandana Soni8Rupesh K. Srivastava9Department of Zoology, School of Biological Sciences, Dr. Harisingh Gour Central University, Sagar (MP)-470003, IndiaDepartment of Pharmaceutical Sciences, Dr. Harisingh Gour Central University, Sagar (MP)-470003, IndiaChitkara School of Health Sciences, Chitkara University, Punjab-140401, IndiaDepartment of Biotechnology, All India Institute of Medical Sciences, (AIIMS), New Delhi-110029, IndiaDepartment of Biotechnology, All India Institute of Medical Sciences, (AIIMS), New Delhi-110029, IndiaDepartment of Biotechnology, All India Institute of Medical Sciences, (AIIMS), New Delhi-110029, IndiaDepartment of Biotechnology, All India Institute of Medical Sciences, (AIIMS), New Delhi-110029, IndiaDepartment of Biotechnology, All India Institute of Medical Sciences, (AIIMS), New Delhi-110029, IndiaDepartment of Pharmaceutical Sciences, Dr. Harisingh Gour Central University, Sagar (MP)-470003, IndiaDepartment of Biotechnology, All India Institute of Medical Sciences, (AIIMS), New Delhi-110029, IndiaOsteoporosis is a progressive and chronic bone disorder characterized by low bone mass and microarchitectural deterioration of skeletal tissues. Osteoporosis leads to alteration in bone mineral content resulting in decreased bone strength with elevated fracture risks frequently associated with greater morbidity. The latest research in the area of photomedicine had sparked interest in harnessing the active components from plants in both disease control and management across the globe. We in the present review have taken a comprehensive approach to identify forty known plants and their phytoconstituents, which encompasses (i) the genetic diversity of various plants, (ii) their active components and (iii) their osteoprotective role in osteoporosis. Thus, the present review is an attempt for the first time to collectively document the therapeutic properties of valuable medicinal plants in preventing and treating bone loss in osteoporosis.https://www.imrpress.com/journal/FBL/25/7/10.2741/4855: phytoconstituentsosteoporosisbone healthbone lossosteo-protective and review |
| spellingShingle | Zaffar Azam Vikas Pandey Navita Gupta Leena Sapra Hamid Y. Dar Niti Shokeen Asha Bhardwaj Ayaan Ahmad Vandana Soni Rupesh K. Srivastava Phytoconstituents as novel osteo-protective agents: Implications in bone health Frontiers in Bioscience-Landmark : phytoconstituents osteoporosis bone health bone loss osteo-protective and review |
| title | Phytoconstituents as novel osteo-protective agents: Implications in bone health |
| title_full | Phytoconstituents as novel osteo-protective agents: Implications in bone health |
| title_fullStr | Phytoconstituents as novel osteo-protective agents: Implications in bone health |
| title_full_unstemmed | Phytoconstituents as novel osteo-protective agents: Implications in bone health |
| title_short | Phytoconstituents as novel osteo-protective agents: Implications in bone health |
| title_sort | phytoconstituents as novel osteo protective agents implications in bone health |
| topic | : phytoconstituents osteoporosis bone health bone loss osteo-protective and review |
| url | https://www.imrpress.com/journal/FBL/25/7/10.2741/4855 |
| work_keys_str_mv | AT zaffarazam phytoconstituentsasnovelosteoprotectiveagentsimplicationsinbonehealth AT vikaspandey phytoconstituentsasnovelosteoprotectiveagentsimplicationsinbonehealth AT navitagupta phytoconstituentsasnovelosteoprotectiveagentsimplicationsinbonehealth AT leenasapra phytoconstituentsasnovelosteoprotectiveagentsimplicationsinbonehealth AT hamidydar phytoconstituentsasnovelosteoprotectiveagentsimplicationsinbonehealth AT nitishokeen phytoconstituentsasnovelosteoprotectiveagentsimplicationsinbonehealth AT ashabhardwaj phytoconstituentsasnovelosteoprotectiveagentsimplicationsinbonehealth AT ayaanahmad phytoconstituentsasnovelosteoprotectiveagentsimplicationsinbonehealth AT vandanasoni phytoconstituentsasnovelosteoprotectiveagentsimplicationsinbonehealth AT rupeshksrivastava phytoconstituentsasnovelosteoprotectiveagentsimplicationsinbonehealth |