PPS, a large multidomain protein, functions with sex-lethal to regulate alternative splicing in Drosophila.

PPS, a large multidomain protein, functions with sex-lethal to regulate alternative splicing in Drosophila.

Alternative splicing controls the expression of many genes, including the Drosophila sex determination gene Sex-lethal (Sxl). Sxl expression is controlled via a negative regulatory mechanism where inclusion of the translation-terminating male exon is blocked in females. Previous studies have shown t...

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Bibliographic Details
Main Authors: Matthew L Johnson, Alexis A Nagengast, Helen K Salz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2832672?pdf=render

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