Selection of optimal quantile protein biomarkers based on cell-level immunohistochemistry data

Selection of optimal quantile protein biomarkers based on cell-level immunohistochemistry data

Abstract Background Protein biomarkers of cancer progression and response to therapy are increasingly important for improving personalized medicine. Advanced quantitative pathology platforms enable measurement of protein expression in tissues at the single-cell level. However, this rich quantitative...

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Bibliographic Details
Main Authors: Misung Yi, Tingting Zhan, Amy R. Peck, Jeffrey A. Hooke, Albert J. Kovatich, Craig D. Shriver, Hai Hu, Yunguang Sun, Hallgeir Rui, Inna Chervoneva
Format: Article
Language:English
Published: BMC 2023-07-01
Series:BMC Bioinformatics
Subjects:
Cellular protein expression
Distribution quantiles
Cancer biomarkers
Tissue microarrays
Breast cancer
Online Access:https://doi.org/10.1186/s12859-023-05408-8

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