Merkel Cell Carcinoma Masquerading Clinically as a Cyst in a Young Patient

Harty Elouise Ashby,1 Grayson N Jones,1 Oon Leedhanachoke,2 Phillip Jen,3 Noah Helphenstine,3 Fadi Al Akhrass4 1Department of Pathology, Pikeville Medical Center, Pikeville, KY, USA; 2Department of General Surgery, Pikeville Medical Center, Pikeville, KY, USA; 3Department of BioMedical Science, Univ...

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Main Authors: Ashby HE, Jones GN, Leedhanachoke O, Jen P, Helphenstine N, Al Akhrass F
Format: Article
Language:English
Published: Dove Medical Press 2024-04-01
Series:International Medical Case Reports Journal
Subjects:
Online Access:https://www.dovepress.com/merkel-cell-carcinoma-masquerading-clinically-as-a-cyst-in-a-young-pat-peer-reviewed-fulltext-article-IMCRJ
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author Ashby HE
Jones GN
Leedhanachoke O
Jen P
Helphenstine N
Al Akhrass F
author_facet Ashby HE
Jones GN
Leedhanachoke O
Jen P
Helphenstine N
Al Akhrass F
author_sort Ashby HE
collection DOAJ
description Harty Elouise Ashby,1 Grayson N Jones,1 Oon Leedhanachoke,2 Phillip Jen,3 Noah Helphenstine,3 Fadi Al Akhrass4 1Department of Pathology, Pikeville Medical Center, Pikeville, KY, USA; 2Department of General Surgery, Pikeville Medical Center, Pikeville, KY, USA; 3Department of BioMedical Science, University of Pikeville, Pikeville, KY, USA; 4Department of Infectious Diseases, Pikeville Medical Center, Pikeville, KY, USACorrespondence: Phillip Jen, Department of BioMedical Science, University of Pikeville, 147 Sycamore Street, Pikeville, KY, 41501, USA, Tel +1 704 488 8258, Email phillipjen@upike.eduAbstract: Merkel cell carcinoma (MCC) is an extremely rare and aggressive tumor. Here we report an unusual MCC that manifested as an abruptly enlarging, painful skin lesion over the right antecubital fossa and masqueraded as an epidermal cyst in a 42-year-old male. The lesion was surgically excised and subjected to histopathologic and immunohistochemical examinations. The subsequent analysis allowed for the diagnosis of MCC. Clinicians should always be cognizant of MCC, which can be easily misdiagnosed. Early diagnosis and appropriate treatment are keys to improving the survival rates of MCC patients.Keywords: Merkel cell carcinoma, histopathologic, immunohistochemical, polyomavirus
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spelling doaj.art-5580c861f9634202a805b4cea6c741732024-04-04T16:51:52ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2024-04-01Volume 1728929391727Merkel Cell Carcinoma Masquerading Clinically as a Cyst in a Young PatientAshby HEJones GNLeedhanachoke OJen PHelphenstine NAl Akhrass FHarty Elouise Ashby,1 Grayson N Jones,1 Oon Leedhanachoke,2 Phillip Jen,3 Noah Helphenstine,3 Fadi Al Akhrass4 1Department of Pathology, Pikeville Medical Center, Pikeville, KY, USA; 2Department of General Surgery, Pikeville Medical Center, Pikeville, KY, USA; 3Department of BioMedical Science, University of Pikeville, Pikeville, KY, USA; 4Department of Infectious Diseases, Pikeville Medical Center, Pikeville, KY, USACorrespondence: Phillip Jen, Department of BioMedical Science, University of Pikeville, 147 Sycamore Street, Pikeville, KY, 41501, USA, Tel +1 704 488 8258, Email phillipjen@upike.eduAbstract: Merkel cell carcinoma (MCC) is an extremely rare and aggressive tumor. Here we report an unusual MCC that manifested as an abruptly enlarging, painful skin lesion over the right antecubital fossa and masqueraded as an epidermal cyst in a 42-year-old male. The lesion was surgically excised and subjected to histopathologic and immunohistochemical examinations. The subsequent analysis allowed for the diagnosis of MCC. Clinicians should always be cognizant of MCC, which can be easily misdiagnosed. Early diagnosis and appropriate treatment are keys to improving the survival rates of MCC patients.Keywords: Merkel cell carcinoma, histopathologic, immunohistochemical, polyomavirushttps://www.dovepress.com/merkel-cell-carcinoma-masquerading-clinically-as-a-cyst-in-a-young-pat-peer-reviewed-fulltext-article-IMCRJmerkel cell carcinomahistopathologicimmunohistochemicalpolyomavirus
spellingShingle Ashby HE
Jones GN
Leedhanachoke O
Jen P
Helphenstine N
Al Akhrass F
Merkel Cell Carcinoma Masquerading Clinically as a Cyst in a Young Patient
International Medical Case Reports Journal
merkel cell carcinoma
histopathologic
immunohistochemical
polyomavirus
title Merkel Cell Carcinoma Masquerading Clinically as a Cyst in a Young Patient
title_full Merkel Cell Carcinoma Masquerading Clinically as a Cyst in a Young Patient
title_fullStr Merkel Cell Carcinoma Masquerading Clinically as a Cyst in a Young Patient
title_full_unstemmed Merkel Cell Carcinoma Masquerading Clinically as a Cyst in a Young Patient
title_short Merkel Cell Carcinoma Masquerading Clinically as a Cyst in a Young Patient
title_sort merkel cell carcinoma masquerading clinically as a cyst in a young patient
topic merkel cell carcinoma
histopathologic
immunohistochemical
polyomavirus
url https://www.dovepress.com/merkel-cell-carcinoma-masquerading-clinically-as-a-cyst-in-a-young-pat-peer-reviewed-fulltext-article-IMCRJ
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