Patients’ perception of the pharmacovigilance system: A pre-diagnostic and post-interventional cross-sectional survey
Background and objective: The risk of adverse reactions necessitated the pharmacovigilance system for patient safety. A literature search documented better health literacy of patients through intervention. This investigation aims to assess the perception and the effect of an intervention on patients...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-11-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2022.936124/full |
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| author | Atta Ur Rehman Atta Ur Rehman Samina Naeem Khalid Rubeena Zakar Ume Hani Muhammad Zakria Zakar Florian Fischer |
| author_facet | Atta Ur Rehman Atta Ur Rehman Samina Naeem Khalid Rubeena Zakar Ume Hani Muhammad Zakria Zakar Florian Fischer |
| author_sort | Atta Ur Rehman |
| collection | DOAJ |
| description | Background and objective: The risk of adverse reactions necessitated the pharmacovigilance system for patient safety. A literature search documented better health literacy of patients through intervention. This investigation aims to assess the perception and the effect of an intervention on patients regarding adverse reactions caused by drugs.Methods: A pre-diagnostic and post-interventional cross-sectional investigation was designed with a sample size of 423 patients in hospitals of Islamabad. The proportion of patients was selected based on a stratified probability technique. A prevalidated tool was used to collect the response twice through a health promotion brochure with counseling, which was applied as an intervention.Results: The outcome of the investigation revealed that the prerequisite of the pharmacovigilance center in the hospital among respondents was improved significantly by 41.2% after intervention. Knowledge, communication, and practice were significantly different with respect to gender. There was a moderate Pearson correlation between diagnostic and interventional responses of patient’s knowledge of adverse reactions by drugs (r = 0.66, p < 0.01) and patient’s communication in pharmacovigilance (r = 0.62, p < 0.01) and a strong correlation between diagnostic and interventional responses of patient’s practice in the pharmacovigilance system (r = 0.72, p < 0.01).Conclusion: The finding of the investigation provided evidence that patient awareness was significantly improved by the health promotion model. Patient participation in the reporting of adverse reactions of drugs will complement the hospital staff reporting. These reports will construct an authentic, cross-checked database for rational drug safety practices in Pakistan. |
| first_indexed | 2024-04-11T08:00:13Z |
| format | Article |
| id | doaj.art-55823b3172844d05836b6e5b0d48ef1e |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-04-11T08:00:13Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-55823b3172844d05836b6e5b0d48ef1e2022-12-22T04:35:44ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122022-11-011310.3389/fphar.2022.936124936124Patients’ perception of the pharmacovigilance system: A pre-diagnostic and post-interventional cross-sectional surveyAtta Ur Rehman0Atta Ur Rehman1Samina Naeem Khalid2Rubeena Zakar3Ume Hani4Muhammad Zakria Zakar5Florian Fischer6Health Services Academy, Quaid e Azam University, Islamabad, PakistanDepartment of Public Health, Institute of Social and Cultural Studies, University of the Punjab, Lahore, PakistanHealth Services Academy, Quaid e Azam University, Islamabad, PakistanDepartment of Public Health, Institute of Social and Cultural Studies, University of the Punjab, Lahore, PakistanHoly Family Hospital, Rawalpindi Medical University, Rawalpindi, PakistanVice Chancellor Office, University of Poonch, Rawalakot, PakistanInstitute of Public Health, Charité—Universitätsmedizin Berlin, Berlin, GermanyBackground and objective: The risk of adverse reactions necessitated the pharmacovigilance system for patient safety. A literature search documented better health literacy of patients through intervention. This investigation aims to assess the perception and the effect of an intervention on patients regarding adverse reactions caused by drugs.Methods: A pre-diagnostic and post-interventional cross-sectional investigation was designed with a sample size of 423 patients in hospitals of Islamabad. The proportion of patients was selected based on a stratified probability technique. A prevalidated tool was used to collect the response twice through a health promotion brochure with counseling, which was applied as an intervention.Results: The outcome of the investigation revealed that the prerequisite of the pharmacovigilance center in the hospital among respondents was improved significantly by 41.2% after intervention. Knowledge, communication, and practice were significantly different with respect to gender. There was a moderate Pearson correlation between diagnostic and interventional responses of patient’s knowledge of adverse reactions by drugs (r = 0.66, p < 0.01) and patient’s communication in pharmacovigilance (r = 0.62, p < 0.01) and a strong correlation between diagnostic and interventional responses of patient’s practice in the pharmacovigilance system (r = 0.72, p < 0.01).Conclusion: The finding of the investigation provided evidence that patient awareness was significantly improved by the health promotion model. Patient participation in the reporting of adverse reactions of drugs will complement the hospital staff reporting. These reports will construct an authentic, cross-checked database for rational drug safety practices in Pakistan.https://www.frontiersin.org/articles/10.3389/fphar.2022.936124/fullpatientsperceptionpharmacovigilancehealth promotionintervention |
| spellingShingle | Atta Ur Rehman Atta Ur Rehman Samina Naeem Khalid Rubeena Zakar Ume Hani Muhammad Zakria Zakar Florian Fischer Patients’ perception of the pharmacovigilance system: A pre-diagnostic and post-interventional cross-sectional survey Frontiers in Pharmacology patients perception pharmacovigilance health promotion intervention |
| title | Patients’ perception of the pharmacovigilance system: A pre-diagnostic and post-interventional cross-sectional survey |
| title_full | Patients’ perception of the pharmacovigilance system: A pre-diagnostic and post-interventional cross-sectional survey |
| title_fullStr | Patients’ perception of the pharmacovigilance system: A pre-diagnostic and post-interventional cross-sectional survey |
| title_full_unstemmed | Patients’ perception of the pharmacovigilance system: A pre-diagnostic and post-interventional cross-sectional survey |
| title_short | Patients’ perception of the pharmacovigilance system: A pre-diagnostic and post-interventional cross-sectional survey |
| title_sort | patients perception of the pharmacovigilance system a pre diagnostic and post interventional cross sectional survey |
| topic | patients perception pharmacovigilance health promotion intervention |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2022.936124/full |
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