颈动脉支架置入术后支架内血栓形成研究进展 Advance in Acute In-stent Thrombosis after Carotid Artery Stenting
【摘要】 颈动脉支架内血栓形成是颈动脉支架置入术后的严重并发症，可导致患者严重瘫痪甚至死亡。然而迄今为止，针对颈动脉支架内血栓形成，仍没有统一的治疗方式。虽然有很多病例报道了颈动脉支架内血栓形成的处理方法，但是仍缺少随机双盲试验或大型临床试验来证实其可靠性、安全性。在临床上，与手术操作相关的颈动脉支架内血栓形成，是颈动脉支架内血栓形成的最主要原因。除此之外，抗血小板治疗不充分或停止抗血小板治疗、高凝状态、抗血小板药物抵抗也可导致颈动脉支架内血栓形成。目前，抗血小板及抗凝治疗、溶栓治疗、颈动脉内膜剥脱术及颈动脉支架术、机械取栓或血栓抽吸治疗等均有报道，无论何种治疗方式，使患者快速获得血管再通是颈...
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| Format: | Article |
| Language: | zho |
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Editorial Department of Chinese Journal of Stroke
2019-06-01
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| Series: | Zhongguo cuzhong zazhi |
| Subjects: | |
| Online Access: | http://www.chinastroke.org.cn/CN/article/openArticlePDF.jsp?id=2805 |
| _version_ | 1818474773322137600 |
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| author | 王翩，王琰，李虹庆 |
| author_facet | 王翩，王琰，李虹庆 |
| author_sort | 王翩，王琰，李虹庆 |
| collection | DOAJ |
| description | 【摘要】 颈动脉支架内血栓形成是颈动脉支架置入术后的严重并发症，可导致患者严重瘫痪甚至死亡。然而迄今为止，针对颈动脉支架内血栓形成，仍没有统一的治疗方式。虽然有很多病例报道了颈动脉支架内血栓形成的处理方法，但是仍缺少随机双盲试验或大型临床试验来证实其可靠性、安全性。在临床上，与手术操作相关的颈动脉支架内血栓形成，是颈动脉支架内血栓形成的最主要原因。除此之外，抗血小板治疗不充分或停止抗血小板治疗、高凝状态、抗血小板药物抵抗也可导致颈动脉支架内血栓形成。目前，抗血小板及抗凝治疗、溶栓治疗、颈动脉内膜剥脱术及颈动脉支架术、机械取栓或血栓抽吸治疗等均有报道，无论何种治疗方式，使患者快速获得血管再通是颈动脉支架内血栓形成治疗的关键。
【Abstract】 In-stent thrombosis is a serious complication after carotid artery stenting (CAS), which may lead to severe paralysis and even death. However, till now, there is still no uniform treatment for in-stent thrombosis. Although cases reports have showed various therapy methods for in-stent thrombosis after CAS, there is still no randomized double-blind trial or large clinical trial to confirm the reliability and safety of these intervention measures. The main cause of instent thrombosis after CAS is related to surgical operation, the other causes include inadequate antiplatelet therapy or discontinuation of antiplatelet therapy, hypercoagulable state, and platelet drug resistance and etc. The treatment for in-stent thrombosis after CAS include antiplatelet and anticoagulant therapy, thrombolytic therapy, carotid endarterectomy and CAS, mechanical thrombectomy or thrombus aspiration and etc. Either way, rapid vascular recanalization is the key of treatment for in-stent thrombosis . |
| first_indexed | 2024-04-14T04:41:44Z |
| format | Article |
| id | doaj.art-55852d2cfc9c4c81be4a314fd125452b |
| institution | Directory Open Access Journal |
| issn | 1673-5765 |
| language | zho |
| last_indexed | 2024-04-14T04:41:44Z |
| publishDate | 2019-06-01 |
| publisher | Editorial Department of Chinese Journal of Stroke |
| record_format | Article |
| series | Zhongguo cuzhong zazhi |
| spelling | doaj.art-55852d2cfc9c4c81be4a314fd125452b2022-12-22T02:11:38ZzhoEditorial Department of Chinese Journal of StrokeZhongguo cuzhong zazhi1673-57652019-06-0114662562910.3969/j.issn.1673-5765.2019.06.020颈动脉支架置入术后支架内血栓形成研究进展 Advance in Acute In-stent Thrombosis after Carotid Artery Stenting王翩，王琰，李虹庆0王琰 17340085006@163.com【摘要】 颈动脉支架内血栓形成是颈动脉支架置入术后的严重并发症，可导致患者严重瘫痪甚至死亡。然而迄今为止，针对颈动脉支架内血栓形成，仍没有统一的治疗方式。虽然有很多病例报道了颈动脉支架内血栓形成的处理方法，但是仍缺少随机双盲试验或大型临床试验来证实其可靠性、安全性。在临床上，与手术操作相关的颈动脉支架内血栓形成，是颈动脉支架内血栓形成的最主要原因。除此之外，抗血小板治疗不充分或停止抗血小板治疗、高凝状态、抗血小板药物抵抗也可导致颈动脉支架内血栓形成。目前，抗血小板及抗凝治疗、溶栓治疗、颈动脉内膜剥脱术及颈动脉支架术、机械取栓或血栓抽吸治疗等均有报道，无论何种治疗方式，使患者快速获得血管再通是颈动脉支架内血栓形成治疗的关键。 【Abstract】 In-stent thrombosis is a serious complication after carotid artery stenting (CAS), which may lead to severe paralysis and even death. However, till now, there is still no uniform treatment for in-stent thrombosis. Although cases reports have showed various therapy methods for in-stent thrombosis after CAS, there is still no randomized double-blind trial or large clinical trial to confirm the reliability and safety of these intervention measures. The main cause of instent thrombosis after CAS is related to surgical operation, the other causes include inadequate antiplatelet therapy or discontinuation of antiplatelet therapy, hypercoagulable state, and platelet drug resistance and etc. The treatment for in-stent thrombosis after CAS include antiplatelet and anticoagulant therapy, thrombolytic therapy, carotid endarterectomy and CAS, mechanical thrombectomy or thrombus aspiration and etc. Either way, rapid vascular recanalization is the key of treatment for in-stent thrombosis .http://www.chinastroke.org.cn/CN/article/openArticlePDF.jsp?id=2805颈动脉支架置入术支架内血栓形成围手术期carotid artery stentingin-stent thrombosisperioperative period |
| spellingShingle | 王翩，王琰，李虹庆 颈动脉支架置入术后支架内血栓形成研究进展 Advance in Acute In-stent Thrombosis after Carotid Artery Stenting Zhongguo cuzhong zazhi 颈动脉支架置入术 支架内血栓形成 围手术期 carotid artery stenting in-stent thrombosis perioperative period |
| title | 颈动脉支架置入术后支架内血栓形成研究进展 Advance in Acute In-stent Thrombosis after Carotid Artery Stenting |
| title_full | 颈动脉支架置入术后支架内血栓形成研究进展 Advance in Acute In-stent Thrombosis after Carotid Artery Stenting |
| title_fullStr | 颈动脉支架置入术后支架内血栓形成研究进展 Advance in Acute In-stent Thrombosis after Carotid Artery Stenting |
| title_full_unstemmed | 颈动脉支架置入术后支架内血栓形成研究进展 Advance in Acute In-stent Thrombosis after Carotid Artery Stenting |
| title_short | 颈动脉支架置入术后支架内血栓形成研究进展 Advance in Acute In-stent Thrombosis after Carotid Artery Stenting |
| title_sort | 颈动脉支架置入术后支架内血栓形成研究进展 advance in acute in stent thrombosis after carotid artery stenting |
| topic | 颈动脉支架置入术 支架内血栓形成 围手术期 carotid artery stenting in-stent thrombosis perioperative period |
| url | http://www.chinastroke.org.cn/CN/article/openArticlePDF.jsp?id=2805 |
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