PET imaging of P2X7R in the experimental autoimmune encephalomyelitis model of multiple sclerosis using [11C]SMW139

PET imaging of P2X7R in the experimental autoimmune encephalomyelitis model of multiple sclerosis using [11C]SMW139

Abstract Background Non-invasive imaging of the activation status of microglia and the ability to identify a pro- or anti-inflammatory environment can provide valuable insights not only into pathogenesis of neuro-inflammatory and neurodegenerative diseases but also the monitoring of the efficacy of...

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Bibliographic Details
Main Authors: Wissam Beaino, Bieneke Janssen, Esther Kooijman, Ricardo Vos, Robert C. Schuit, James O’Brien-Brown, Michael Kassiou, Bert van het Hof, Danielle J. Vugts, Helga E. de Vries, Albert D. Windhorst
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Journal of Neuroinflammation
Subjects:
Microglia
Neuro-inflammation
PET imaging
P2X7R
Multiple sclerosis
Online Access:http://link.springer.com/article/10.1186/s12974-020-01962-7

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