Changes of D dimer in women with gestational diabetes and healthy women after elective cesarean section
Introduction: Due to the increasing prevalence of gestational diabetes, which is one of the indications for cesarean section, and both of these cases have adverse effects on the coagulation pathway, this study was performed with aim to compare the level of D-dimer in two groups of healthy and diabet...
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| Format: | Article |
| Language: | fas |
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Mashhad University of Medical Sciences
2021-11-01
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| Series: | Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān |
| Subjects: | |
| Online Access: | https://ijogi.mums.ac.ir/article_19383_d092d2c304c15bd2559e4df374142e9b.pdf |
| _version_ | 1798044434986696704 |
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| author | Fatemeh Mallah Mina Zeinalzadeh Dara Alvandfar |
| author_facet | Fatemeh Mallah Mina Zeinalzadeh Dara Alvandfar |
| author_sort | Fatemeh Mallah |
| collection | DOAJ |
| description | Introduction: Due to the increasing prevalence of gestational diabetes, which is one of the indications for cesarean section, and both of these cases have adverse effects on the coagulation pathway, this study was performed with aim to compare the level of D-dimer in two groups of healthy and diabetic pregnant women after cesarean section to assess the coagulation risks after cesarean section.
Methods: This descriptive study was performed in 2019 on 150 healthy and gestational diabetes women who were candidates for elective cesarean section in 2019. The level of D-dimer was measured on the day before surgery, the day after surgery, on the seventh and fourteenth days for both groups. Data were analyzed by SPSS software (version 22) and Independent t-test, Chi-square, regression and Spearman correlation tests. P<0.05 was considered statistically significant.
Results: The level of D-dimer on the day after surgery had the most statistically significant difference between healthy and gestational diabetes women (P=0.001). Also, on seven days after surgery (P=0.012) and 14 days after surgery (P=0.039), the amount of D-dimer was significantly higher in women with gestational diabetes than healthy women. It was also found that smoking (P=0.031) and previous history of pregnancy (P=0.041) were significantly associated with increased D-dimer levels in women with gestational diabetes.
Conclusion: Gestational diabetes plays a role in increasing the level of D-dimer and can lead to an increase in plasma level of D-dimer. |
| first_indexed | 2024-04-11T23:05:20Z |
| format | Article |
| id | doaj.art-558fcd624fb74afead45d822279a44ef |
| institution | Directory Open Access Journal |
| issn | 1680-2993 2008-2363 |
| language | fas |
| last_indexed | 2024-04-11T23:05:20Z |
| publishDate | 2021-11-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān |
| spelling | doaj.art-558fcd624fb74afead45d822279a44ef2022-12-22T03:58:03ZfasMashhad University of Medical SciencesMajallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān1680-29932008-23632021-11-0124101710.22038/ijogi.2021.1938319383Changes of D dimer in women with gestational diabetes and healthy women after elective cesarean sectionFatemeh Mallah0Mina Zeinalzadeh1Dara Alvandfar2Associate Professor, Department of Gynecology Surgery, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.B.Sc. student of Anesthesia, School of Paramedical, Tabriz University of Medical Sciences, Tabriz, Iran.Assistant Professor, Department of General and Vascular Surgery, Comfortable Breathing and Sleep Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.Introduction: Due to the increasing prevalence of gestational diabetes, which is one of the indications for cesarean section, and both of these cases have adverse effects on the coagulation pathway, this study was performed with aim to compare the level of D-dimer in two groups of healthy and diabetic pregnant women after cesarean section to assess the coagulation risks after cesarean section. Methods: This descriptive study was performed in 2019 on 150 healthy and gestational diabetes women who were candidates for elective cesarean section in 2019. The level of D-dimer was measured on the day before surgery, the day after surgery, on the seventh and fourteenth days for both groups. Data were analyzed by SPSS software (version 22) and Independent t-test, Chi-square, regression and Spearman correlation tests. P<0.05 was considered statistically significant. Results: The level of D-dimer on the day after surgery had the most statistically significant difference between healthy and gestational diabetes women (P=0.001). Also, on seven days after surgery (P=0.012) and 14 days after surgery (P=0.039), the amount of D-dimer was significantly higher in women with gestational diabetes than healthy women. It was also found that smoking (P=0.031) and previous history of pregnancy (P=0.041) were significantly associated with increased D-dimer levels in women with gestational diabetes. Conclusion: Gestational diabetes plays a role in increasing the level of D-dimer and can lead to an increase in plasma level of D-dimer.https://ijogi.mums.ac.ir/article_19383_d092d2c304c15bd2559e4df374142e9b.pdfcesarean sectiond-dimergestational diabetesdeep vein thrombosis |
| spellingShingle | Fatemeh Mallah Mina Zeinalzadeh Dara Alvandfar Changes of D dimer in women with gestational diabetes and healthy women after elective cesarean section Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān cesarean section d-dimer gestational diabetes deep vein thrombosis |
| title | Changes of D dimer in women with gestational diabetes and healthy women after elective cesarean section |
| title_full | Changes of D dimer in women with gestational diabetes and healthy women after elective cesarean section |
| title_fullStr | Changes of D dimer in women with gestational diabetes and healthy women after elective cesarean section |
| title_full_unstemmed | Changes of D dimer in women with gestational diabetes and healthy women after elective cesarean section |
| title_short | Changes of D dimer in women with gestational diabetes and healthy women after elective cesarean section |
| title_sort | changes of d dimer in women with gestational diabetes and healthy women after elective cesarean section |
| topic | cesarean section d-dimer gestational diabetes deep vein thrombosis |
| url | https://ijogi.mums.ac.ir/article_19383_d092d2c304c15bd2559e4df374142e9b.pdf |
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