What is changing in indications and treatment of hepatic hemangiomas. A review
Hepatic cavernous hemangioma accounts for 73% of all benign liver tumors with a frequency of 0.4-7.3% at autopsy and is the second most common tumor seen in the liver after metastases. Patients affected by hemangioma usually have their tumor diagnosed by ultrasound abdominal examination for a not we...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2014-07-01
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| Series: | Annals of Hepatology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1665268119308397 |
| _version_ | 1829514123807817728 |
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| author | Adriana Toro Ahmed-Emad Mahfouz Annalisa Ardiri Michele Malaguarnera Giulia Malaguarnera Francesco Loria Gaetano Bertino Isidoro Di Carlo |
| author_facet | Adriana Toro Ahmed-Emad Mahfouz Annalisa Ardiri Michele Malaguarnera Giulia Malaguarnera Francesco Loria Gaetano Bertino Isidoro Di Carlo |
| author_sort | Adriana Toro |
| collection | DOAJ |
| description | Hepatic cavernous hemangioma accounts for 73% of all benign liver tumors with a frequency of 0.4-7.3% at autopsy and is the second most common tumor seen in the liver after metastases. Patients affected by hemangioma usually have their tumor diagnosed by ultrasound abdominal examination for a not well defined pain, but pain persist after treatment of the hemangioma. The causes of pain can be various gastrointestinal pathologies including cholelithiasis and peptic ulcer disease.The malignant trasformation is pratically inexistent. Different imaging modalities are used to diagnosis liver hemangioma including ultrasonography, computed tomography (CT), magnetic resonance (MR) imaging, and less frequently scintigraphy, positron-emission tomography combined with CT (PET/CT) and angiography. Imaging-guided biopsy of hemangioma is usually not resorted to except in extremely atypical cases. The right indications for surgery remain rupture, intratumoral bleeding, Kasabach-Merritt syndrome and organ or vessels compression (gastric outlet obstruction, Budd-Chiari syndrome, etc.) represents the valid indication for surgery and at the same time they are all complications of the tumor itself. The size of the tumor do not represent a valid indication for treatment. Liver hemangiomas, when indication exist, have to be treated firstly by surgery (hepatic resection or enucleation, open, laproscopic or robotic), but in the recent years other therapies like liver transplantation, radiofrequency ablation, radiotherapy, trans-arterial embolization, and chemotherapy have been applied. |
| first_indexed | 2024-12-16T13:12:15Z |
| format | Article |
| id | doaj.art-5593e97b78db457baf464e06e082bbdd |
| institution | Directory Open Access Journal |
| issn | 1665-2681 |
| language | English |
| last_indexed | 2024-12-16T13:12:15Z |
| publishDate | 2014-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Annals of Hepatology |
| spelling | doaj.art-5593e97b78db457baf464e06e082bbdd2022-12-21T22:30:34ZengElsevierAnnals of Hepatology1665-26812014-07-01134327339What is changing in indications and treatment of hepatic hemangiomas. A reviewAdriana Toro0Ahmed-Emad Mahfouz1Annalisa Ardiri2Michele Malaguarnera3Giulia Malaguarnera4Francesco Loria5Gaetano Bertino6Isidoro Di Carlo7Department of Surgery, Taormina Hospital, Messina, ItalyDepartment of Radiology, Hamad General Hospital, Doha QatarHepatology Unit. Department of Medical and Pediatric Science, University of Catania, ItalyInternational PhD Program in Neuropharmacology. University of Catania, ItalyUniversity of Catania; Research Center “The Great Senescence”. Cannizzaro Hospital, ItalyDepartment of Radiology PO Palmi, ASP 5 RC, ItalyHepatology Unit. Department of Medical and Pediatric Science, University of Catania, ItalyDepartment of Surgical Sciences, Organ Transplantation and Advanced Technologies, University of Catania. Catania, Italy; Department of Radiology, Hamad General Hospital, Doha Qatar; Department of Surgery, Hamad Medical Hospital, Doha, Qatar; Correspondence and reprint request:Hepatic cavernous hemangioma accounts for 73% of all benign liver tumors with a frequency of 0.4-7.3% at autopsy and is the second most common tumor seen in the liver after metastases. Patients affected by hemangioma usually have their tumor diagnosed by ultrasound abdominal examination for a not well defined pain, but pain persist after treatment of the hemangioma. The causes of pain can be various gastrointestinal pathologies including cholelithiasis and peptic ulcer disease.The malignant trasformation is pratically inexistent. Different imaging modalities are used to diagnosis liver hemangioma including ultrasonography, computed tomography (CT), magnetic resonance (MR) imaging, and less frequently scintigraphy, positron-emission tomography combined with CT (PET/CT) and angiography. Imaging-guided biopsy of hemangioma is usually not resorted to except in extremely atypical cases. The right indications for surgery remain rupture, intratumoral bleeding, Kasabach-Merritt syndrome and organ or vessels compression (gastric outlet obstruction, Budd-Chiari syndrome, etc.) represents the valid indication for surgery and at the same time they are all complications of the tumor itself. The size of the tumor do not represent a valid indication for treatment. Liver hemangiomas, when indication exist, have to be treated firstly by surgery (hepatic resection or enucleation, open, laproscopic or robotic), but in the recent years other therapies like liver transplantation, radiofrequency ablation, radiotherapy, trans-arterial embolization, and chemotherapy have been applied.http://www.sciencedirect.com/science/article/pii/S1665268119308397Hepatic surgeryHemangiomas of the liverRadiofrequency ablationBenign tumors of the lliverHepatic transplantation |
| spellingShingle | Adriana Toro Ahmed-Emad Mahfouz Annalisa Ardiri Michele Malaguarnera Giulia Malaguarnera Francesco Loria Gaetano Bertino Isidoro Di Carlo What is changing in indications and treatment of hepatic hemangiomas. A review Annals of Hepatology Hepatic surgery Hemangiomas of the liver Radiofrequency ablation Benign tumors of the lliver Hepatic transplantation |
| title | What is changing in indications and treatment of hepatic hemangiomas. A review |
| title_full | What is changing in indications and treatment of hepatic hemangiomas. A review |
| title_fullStr | What is changing in indications and treatment of hepatic hemangiomas. A review |
| title_full_unstemmed | What is changing in indications and treatment of hepatic hemangiomas. A review |
| title_short | What is changing in indications and treatment of hepatic hemangiomas. A review |
| title_sort | what is changing in indications and treatment of hepatic hemangiomas a review |
| topic | Hepatic surgery Hemangiomas of the liver Radiofrequency ablation Benign tumors of the lliver Hepatic transplantation |
| url | http://www.sciencedirect.com/science/article/pii/S1665268119308397 |
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