Characterization of the conserved regions of E1A protein from human adenovirus for reinforcement of cytotoxic T lymphocytes responses to the all genogroups causes ocular manifestation through an in silico approach

Characterization of the conserved regions of E1A protein from human adenovirus for reinforcement of cytotoxic T lymphocytes responses to the all genogroups causes ocular manifestation through an in silico approach

Background and Objectives: Adenovirus species B, C, D, and E are the most common causes of ocular manifestations caused by adenoviruses. FDA-approved treatment agents for adenovirus infections are not available. Cell-mediated immunity is the major protective mechanism versus human adenoviruses (HAd...

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Bibliographic Details
Main Authors: Nahid Omidi, Azarakhsh Azaran, Manoochehr Makvandi, Gholamreza Khataminia, Kambiz Ahmadi Angali, Shahram Jalilian
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2022-10-01
Series:Iranian Journal of Microbiology
Subjects:
In silico model;
Adenovirus E1A proteins;
Keratoconjunctivitis;
Molecular docking;
Cytotoxic T-lymphocyte
Online Access:https://ijm.tums.ac.ir/index.php/ijm/article/view/3419

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