Time to death and its predictors among neonates who were admitted to the neonatal intensive care unit at tertiary hospital, Addis Ababa, Ethiopia: Retrospective follow up study
BackgroundsNeonatal death is the major problem in developing world. Burden and predictors of neonatal mortality vary across countries and even among regions of a country, so understanding the problem concerning these factors is essential to overcome the problem. Therefore, this study aimed to determ...
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2022.913583/full |
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| author | Mulat Mossie Menalu Bereket Gebremichael Kalkidan Wondwossen Desta Worku Misganaw Kebede Fetene Nigussie Tarekegn Getaneh Baye Mulu Getaneh Baye Mulu Bantalem Tilaye Atinafu |
| author_facet | Mulat Mossie Menalu Bereket Gebremichael Kalkidan Wondwossen Desta Worku Misganaw Kebede Fetene Nigussie Tarekegn Getaneh Baye Mulu Getaneh Baye Mulu Bantalem Tilaye Atinafu |
| author_sort | Mulat Mossie Menalu |
| collection | DOAJ |
| description | BackgroundsNeonatal death is the major problem in developing world. Burden and predictors of neonatal mortality vary across countries and even among regions of a country, so understanding the problem concerning these factors is essential to overcome the problem. Therefore, this study aimed to determine time to death and its predictors of neonatal mortality among neonates who were admitted to the neonatal intensive care unit of Tertiary Hospital, Addis Ababa, Ethiopia.MethodsA hospital-based retrospective cohort study was employed among 434 neonates admitted in Tertiary hospital, Addis Ababa, Ethiopia. A Kaplan Meier curve and a log-rank test were used to estimate the survival time and compare survival curves between variables. The cox proportional hazard model was also fitted to identify predictors.ResultsA total of 434 neonates included in the study, 11.1% of which were died, and the incidence rate was 19.2 per 1000 live births. The time to death of neonates was 17 days. Independent predictors of neonatal mortality were incomplete maternal antenatal follow up[AHR: 3.7 (95% CI:1.86,7.60)], low(Appearance, Pulse, Grimily, Activity, and Respiration(APGAR)score[AHR:5.0 (95%CI:1.51–15.04)], perinatal asphyxia [AHR:5.2 (95%CI:1.92–14.30)], preterm 4.2 (95%CI: 1.32–8.83)]. Moreover, small for gestational age [AHR:4.8 (95%CI:2.33–9.72)], respiratory distress[AHR: 2.5 (95%CI: 1.24–5.09)], sepsis [AHR: 3.4 (95%CI: 1.71–4.01)], low birth weight[AHR: 7.3 (95%CI:2.69,1.91)], and tracheoesophageal fistula [AHR: 2.2 (95%CI: 1.13–4.32)].ConclusionThe overall incidence rate was 19.2 deaths per 1,000 live births. Emphasis should be given to incomplete Antenatal care follow up, small for gestation, preterm, low birth weight, low 5th min APGAR score, neonatal sepsis, respiratory distress, perinatal asphyxia, and tracheoesophageal fistula. |
| first_indexed | 2024-04-13T17:31:23Z |
| format | Article |
| id | doaj.art-55a099e0541c42789d4bb6554815d78e |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-04-13T17:31:23Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Pediatrics |
| spelling | doaj.art-55a099e0541c42789d4bb6554815d78e2022-12-22T02:37:33ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602022-08-011010.3389/fped.2022.913583913583Time to death and its predictors among neonates who were admitted to the neonatal intensive care unit at tertiary hospital, Addis Ababa, Ethiopia: Retrospective follow up studyMulat Mossie Menalu0Bereket Gebremichael1Kalkidan Wondwossen Desta2Worku Misganaw Kebede3Fetene Nigussie Tarekegn4Getaneh Baye Mulu5Getaneh Baye Mulu6Bantalem Tilaye Atinafu7School of Nursing and Midwifery, Asrat Weldeyes Health Science, Debre Berhan University, Debre Berhan, EthiopiaCollege of Health Sciences, Addis Ababa University, Addis Ababa, EthiopiaDepartment of Pediatrics and Child Health Nursing, School of Nursing and Midwifery, Institute of Medicine and Health Science, Addis Ababa University, Addis Ababa, EthiopiaSchool of Nursing and Midwifery, Asrat Weldeyes Health Science, Debre Berhan University, Debre Berhan, EthiopiaSchool of Nursing and Midwifery, Asrat Weldeyes Health Science, Debre Berhan University, Debre Berhan, EthiopiaSchool of Nursing and Midwifery, Asrat Weldeyes Health Science, Debre Berhan University, Debre Berhan, EthiopiaClinical and Pyschosocial Epidemiology, Faculty of Medical Sciences, University of Groningen, Groningen, NetherlandsSchool of Nursing and Midwifery, Asrat Weldeyes Health Science, Debre Berhan University, Debre Berhan, EthiopiaBackgroundsNeonatal death is the major problem in developing world. Burden and predictors of neonatal mortality vary across countries and even among regions of a country, so understanding the problem concerning these factors is essential to overcome the problem. Therefore, this study aimed to determine time to death and its predictors of neonatal mortality among neonates who were admitted to the neonatal intensive care unit of Tertiary Hospital, Addis Ababa, Ethiopia.MethodsA hospital-based retrospective cohort study was employed among 434 neonates admitted in Tertiary hospital, Addis Ababa, Ethiopia. A Kaplan Meier curve and a log-rank test were used to estimate the survival time and compare survival curves between variables. The cox proportional hazard model was also fitted to identify predictors.ResultsA total of 434 neonates included in the study, 11.1% of which were died, and the incidence rate was 19.2 per 1000 live births. The time to death of neonates was 17 days. Independent predictors of neonatal mortality were incomplete maternal antenatal follow up[AHR: 3.7 (95% CI:1.86,7.60)], low(Appearance, Pulse, Grimily, Activity, and Respiration(APGAR)score[AHR:5.0 (95%CI:1.51–15.04)], perinatal asphyxia [AHR:5.2 (95%CI:1.92–14.30)], preterm 4.2 (95%CI: 1.32–8.83)]. Moreover, small for gestational age [AHR:4.8 (95%CI:2.33–9.72)], respiratory distress[AHR: 2.5 (95%CI: 1.24–5.09)], sepsis [AHR: 3.4 (95%CI: 1.71–4.01)], low birth weight[AHR: 7.3 (95%CI:2.69,1.91)], and tracheoesophageal fistula [AHR: 2.2 (95%CI: 1.13–4.32)].ConclusionThe overall incidence rate was 19.2 deaths per 1,000 live births. Emphasis should be given to incomplete Antenatal care follow up, small for gestation, preterm, low birth weight, low 5th min APGAR score, neonatal sepsis, respiratory distress, perinatal asphyxia, and tracheoesophageal fistula.https://www.frontiersin.org/articles/10.3389/fped.2022.913583/fullneonatal mortalitysurvival statustime to deathpredictorsEthiopia |
| spellingShingle | Mulat Mossie Menalu Bereket Gebremichael Kalkidan Wondwossen Desta Worku Misganaw Kebede Fetene Nigussie Tarekegn Getaneh Baye Mulu Getaneh Baye Mulu Bantalem Tilaye Atinafu Time to death and its predictors among neonates who were admitted to the neonatal intensive care unit at tertiary hospital, Addis Ababa, Ethiopia: Retrospective follow up study Frontiers in Pediatrics neonatal mortality survival status time to death predictors Ethiopia |
| title | Time to death and its predictors among neonates who were admitted to the neonatal intensive care unit at tertiary hospital, Addis Ababa, Ethiopia: Retrospective follow up study |
| title_full | Time to death and its predictors among neonates who were admitted to the neonatal intensive care unit at tertiary hospital, Addis Ababa, Ethiopia: Retrospective follow up study |
| title_fullStr | Time to death and its predictors among neonates who were admitted to the neonatal intensive care unit at tertiary hospital, Addis Ababa, Ethiopia: Retrospective follow up study |
| title_full_unstemmed | Time to death and its predictors among neonates who were admitted to the neonatal intensive care unit at tertiary hospital, Addis Ababa, Ethiopia: Retrospective follow up study |
| title_short | Time to death and its predictors among neonates who were admitted to the neonatal intensive care unit at tertiary hospital, Addis Ababa, Ethiopia: Retrospective follow up study |
| title_sort | time to death and its predictors among neonates who were admitted to the neonatal intensive care unit at tertiary hospital addis ababa ethiopia retrospective follow up study |
| topic | neonatal mortality survival status time to death predictors Ethiopia |
| url | https://www.frontiersin.org/articles/10.3389/fped.2022.913583/full |
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