Optical coherence tomography in patients with somatotropin-producing pituitary adenoma

Optical coherence tomography (OCT) is widely used in ophthalmological practice. The review presents the results of OCT in patients with somatotropin-producing pituitary adenoma, or somatotropinoma, which is a hormone-active tumor of the adenohypophysis, characterized by excessive production of somat...

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Main Authors: N. A. Gavrilova, N. S. Gadzhieva, A. V. Kuz’mina
Format: Article
Language:Russian
Published: Real Time Ltd 2021-06-01
Series:Российский офтальмологический журнал
Subjects:
Online Access:https://roj.igb.ru/jour/article/view/664
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author N. A. Gavrilova
N. S. Gadzhieva
A. V. Kuz’mina
author_facet N. A. Gavrilova
N. S. Gadzhieva
A. V. Kuz’mina
author_sort N. A. Gavrilova
collection DOAJ
description Optical coherence tomography (OCT) is widely used in ophthalmological practice. The review presents the results of OCT in patients with somatotropin-producing pituitary adenoma, or somatotropinoma, which is a hormone-active tumor of the adenohypophysis, characterized by excessive production of somatotropic hormone (STH). It stimulates the secretion of type I insulin-like growth factor (IGF-I). The mechanisms of STH action (pro-angiogenic action, stimulation endothelial cell proliferation and migration, development of endothelial dysfunction and retinal edema) requires much attention to the results of examination of patients with somatotropinomas using modern diagnostic methods, such as OCT.
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spelling doaj.art-55a2b9a2595c491cae86b316cbf1ef7c2023-03-13T07:54:31ZrusReal Time LtdРоссийский офтальмологический журнал2072-00762587-57602021-06-01142818410.21516/2072-0076-2021-14-2-81-84360Optical coherence tomography in patients with somatotropin-producing pituitary adenomaN. A. Gavrilova0N. S. Gadzhieva1A. V. Kuz’mina2ФГБОУ ВО «МГМСУ им. А.И. Евдокимова» Минздрава РоссииФГБОУ ВО «МГМСУ им. А.И. Евдокимова» Минздрава РоссииФГБОУ ВО «МГМСУ им. А.И. Евдокимова» Минздрава РоссииOptical coherence tomography (OCT) is widely used in ophthalmological practice. The review presents the results of OCT in patients with somatotropin-producing pituitary adenoma, or somatotropinoma, which is a hormone-active tumor of the adenohypophysis, characterized by excessive production of somatotropic hormone (STH). It stimulates the secretion of type I insulin-like growth factor (IGF-I). The mechanisms of STH action (pro-angiogenic action, stimulation endothelial cell proliferation and migration, development of endothelial dysfunction and retinal edema) requires much attention to the results of examination of patients with somatotropinomas using modern diagnostic methods, such as OCT.https://roj.igb.ru/jour/article/view/664оптическая когерентная томографиясоматотропиномадиагностика
spellingShingle N. A. Gavrilova
N. S. Gadzhieva
A. V. Kuz’mina
Optical coherence tomography in patients with somatotropin-producing pituitary adenoma
Российский офтальмологический журнал
оптическая когерентная томография
соматотропинома
диагностика
title Optical coherence tomography in patients with somatotropin-producing pituitary adenoma
title_full Optical coherence tomography in patients with somatotropin-producing pituitary adenoma
title_fullStr Optical coherence tomography in patients with somatotropin-producing pituitary adenoma
title_full_unstemmed Optical coherence tomography in patients with somatotropin-producing pituitary adenoma
title_short Optical coherence tomography in patients with somatotropin-producing pituitary adenoma
title_sort optical coherence tomography in patients with somatotropin producing pituitary adenoma
topic оптическая когерентная томография
соматотропинома
диагностика
url https://roj.igb.ru/jour/article/view/664
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AT nsgadzhieva opticalcoherencetomographyinpatientswithsomatotropinproducingpituitaryadenoma
AT avkuzmina opticalcoherencetomographyinpatientswithsomatotropinproducingpituitaryadenoma