Systemic lupus erythematosus and myelofibrosis: A case report and revision of literature

Blood cytopenia represents one of the diagnostic criteria for systemic lupus erythematosus (SLE) and may occur as the first symptom of the disease. Antibody-mediated peripheral destruction of blood cells is the main cause of cytopenia observed in patients affected by SLE, however, inflammatory anemi...

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Main Authors: F. Del Porto, C. Tatarelli, A. Di Napoli, M. Proietta
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Leukemia Research Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213048918300116
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author F. Del Porto
C. Tatarelli
A. Di Napoli
M. Proietta
author_facet F. Del Porto
C. Tatarelli
A. Di Napoli
M. Proietta
author_sort F. Del Porto
collection DOAJ
description Blood cytopenia represents one of the diagnostic criteria for systemic lupus erythematosus (SLE) and may occur as the first symptom of the disease. Antibody-mediated peripheral destruction of blood cells is the main cause of cytopenia observed in patients affected by SLE, however, inflammatory anemia, nutritional deficiencies, immunosuppressive therapy and, more rarely, myelofibrosis (MF) have also been documented. In the literature, 45 cases of autoimmune MF (AIMF) and SLE have been previously reported. Here the 46th case of a 43-year-old female with a SLE and an underhand cytopenia, with a review of the literature. Keywords: Systemic lupus erythematosus, Autoimmune myelofibrosis, Blood cytopenia
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spelling doaj.art-55a5be7b424644699d906b54f83cf9c42022-12-21T18:12:52ZengElsevierLeukemia Research Reports2213-04892018-01-0195864Systemic lupus erythematosus and myelofibrosis: A case report and revision of literatureF. Del Porto0C. Tatarelli1A. Di Napoli2M. Proietta3Sapienza Università di Roma, Facoltà di Medicina e Psicologia, Dipartimento di Medicina Clinica e Molecolare, UOC Medicina Interna, Ospedale Sant’Andrea, Via di Grottarossa 1035-1039, 00189 Rome, Italy; Corresponding author.Sapienza Università di Roma, Facoltà di Medicina e Psicologia, Dipartimento di Medicina Clinica e Molecolare, UOC Ematologia, Ospedale Sant’Andrea, Rome, ItalySapienza Università di Roma, Facoltà di Medicina e Psicologia, Dipartimento di Medicina Clinica e Molecolare, UOC Anatomia Patologica, Ospedale Sant’Andrea, Rome, ItalySapienza Università di Roma, Facoltà di Medicina e Psicologia, Dipartimento di Medicina Clinica e Molecolare, UOC Medicina Interna, Ospedale Sant’Andrea, Via di Grottarossa 1035-1039, 00189 Rome, ItalyBlood cytopenia represents one of the diagnostic criteria for systemic lupus erythematosus (SLE) and may occur as the first symptom of the disease. Antibody-mediated peripheral destruction of blood cells is the main cause of cytopenia observed in patients affected by SLE, however, inflammatory anemia, nutritional deficiencies, immunosuppressive therapy and, more rarely, myelofibrosis (MF) have also been documented. In the literature, 45 cases of autoimmune MF (AIMF) and SLE have been previously reported. Here the 46th case of a 43-year-old female with a SLE and an underhand cytopenia, with a review of the literature. Keywords: Systemic lupus erythematosus, Autoimmune myelofibrosis, Blood cytopeniahttp://www.sciencedirect.com/science/article/pii/S2213048918300116
spellingShingle F. Del Porto
C. Tatarelli
A. Di Napoli
M. Proietta
Systemic lupus erythematosus and myelofibrosis: A case report and revision of literature
Leukemia Research Reports
title Systemic lupus erythematosus and myelofibrosis: A case report and revision of literature
title_full Systemic lupus erythematosus and myelofibrosis: A case report and revision of literature
title_fullStr Systemic lupus erythematosus and myelofibrosis: A case report and revision of literature
title_full_unstemmed Systemic lupus erythematosus and myelofibrosis: A case report and revision of literature
title_short Systemic lupus erythematosus and myelofibrosis: A case report and revision of literature
title_sort systemic lupus erythematosus and myelofibrosis a case report and revision of literature
url http://www.sciencedirect.com/science/article/pii/S2213048918300116
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