The Intersection of Age and Influenza Severity: Utility of Ferrets for Dissecting the Age-Dependent Immune Responses and Relevance to Age-Specific Vaccine Development

The Intersection of Age and Influenza Severity: Utility of Ferrets for Dissecting the Age-Dependent Immune Responses and Relevance to Age-Specific Vaccine Development

Many factors impact the host response to influenza virus infection and vaccination. Ferrets have been an indispensable reagent for influenza virus research for almost one hundred years. One of the most significant and well-known factors affecting human disease after infection is host age. Another si...

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Bibliographic Details
Main Authors: Melissa Rioux, Magen E. Francis, Cynthia L. Swan, Anni Ge, Andrea Kroeker, Alyson A. Kelvin
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Viruses
Subjects:
ferret
preclinical model
influenza
respiratory viruses
age-related disease
risk-factors
Online Access:https://www.mdpi.com/1999-4915/13/4/678

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