Risk factors for delayed cerebral infarction after intracranial aneurysm clipping
Objective To analyze the risk factors and clinical significance of delayed cerebral infarction (DCI) after intracranial aneurysm (IA) clipping. Methods A retrospective analysis was performed on the clinical data of IA patients admitted to the First Affiliated Hospital of Chongqing Medical University...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of Third Military Medical University
2021-04-01
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| Series: | Di-san junyi daxue xuebao |
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| Online Access: | https://aammt.tmmu.edu.cn/Upload/rhtml/202011256.htm |
| _version_ | 1819104030167662592 |
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| author | SU Jun SU Jun HAUNG Hao XIN Yuanjun WU Xintong YANG Xiaolin HE Zhaohui |
| author_facet | SU Jun SU Jun HAUNG Hao XIN Yuanjun WU Xintong YANG Xiaolin HE Zhaohui |
| author_sort | SU Jun |
| collection | DOAJ |
| description | Objective To analyze the risk factors and clinical significance of delayed cerebral infarction (DCI) after intracranial aneurysm (IA) clipping. Methods A retrospective analysis was performed on the clinical data of IA patients admitted to the First Affiliated Hospital of Chongqing Medical University from January 2015 to December 2019. A total of 480 patients undergoing aneurysm clipping were included. The patients with DCI were set as the observation group (n=42), and those without as the control group (n=438). The risk factors for DCI were screened by univariate and multivariate logistic regression analysis. Results Univariate analysis showed that female (P=0.029), small aneurysms (P=0.001), intraoperative aneurysm rupture (IAR) (P=0.007) and cerebral vasospasm (P < 0.001) were risk factors for DCI after IA clipping, while smoking history (P=0.020) was a protective factor. Multivariate logistic regression analysis indicated that small aneurysms (P=0.002, OR=2.951, 95%CI: 1.478~5.893), IAR (P=0.004, OR=7.829, 95%CI: 1.924~31.854) and cerebral vasospasm (P < 0.001, OR=5.919, 95%CI: 2.887~12.134) were postoperative independent risk factors for DCI. Conclusion Proper treatment of small aneurysms, proactive prevention of IAR and treatment of cerebral vasospasm can prevent the occurrence of DCI effectively, and thereby reduce the disability rate and improve the prognosis of patients. |
| first_indexed | 2024-12-22T01:59:52Z |
| format | Article |
| id | doaj.art-55a6f04a67c94ba78cd268b302943eaa |
| institution | Directory Open Access Journal |
| issn | 1000-5404 |
| language | zho |
| last_indexed | 2024-12-22T01:59:52Z |
| publishDate | 2021-04-01 |
| publisher | Editorial Office of Journal of Third Military Medical University |
| record_format | Article |
| series | Di-san junyi daxue xuebao |
| spelling | doaj.art-55a6f04a67c94ba78cd268b302943eaa2022-12-21T18:42:41ZzhoEditorial Office of Journal of Third Military Medical UniversityDi-san junyi daxue xuebao1000-54042021-04-0143763563910.16016/j.1000-5404.202011256Risk factors for delayed cerebral infarction after intracranial aneurysm clippingSU Jun0SU Jun1HAUNG Hao2XIN Yuanjun3WU Xintong4YANG Xiaolin5HE Zhaohui6Department of Neurosurgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016;Department of Neurosurgery, Nanchuan People's Hospital, Chongqing, 408400, China Department of Neurosurgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016Department of Neurosurgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016Department of Neurosurgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016Department of Neurosurgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016Department of Neurosurgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016Objective To analyze the risk factors and clinical significance of delayed cerebral infarction (DCI) after intracranial aneurysm (IA) clipping. Methods A retrospective analysis was performed on the clinical data of IA patients admitted to the First Affiliated Hospital of Chongqing Medical University from January 2015 to December 2019. A total of 480 patients undergoing aneurysm clipping were included. The patients with DCI were set as the observation group (n=42), and those without as the control group (n=438). The risk factors for DCI were screened by univariate and multivariate logistic regression analysis. Results Univariate analysis showed that female (P=0.029), small aneurysms (P=0.001), intraoperative aneurysm rupture (IAR) (P=0.007) and cerebral vasospasm (P < 0.001) were risk factors for DCI after IA clipping, while smoking history (P=0.020) was a protective factor. Multivariate logistic regression analysis indicated that small aneurysms (P=0.002, OR=2.951, 95%CI: 1.478~5.893), IAR (P=0.004, OR=7.829, 95%CI: 1.924~31.854) and cerebral vasospasm (P < 0.001, OR=5.919, 95%CI: 2.887~12.134) were postoperative independent risk factors for DCI. Conclusion Proper treatment of small aneurysms, proactive prevention of IAR and treatment of cerebral vasospasm can prevent the occurrence of DCI effectively, and thereby reduce the disability rate and improve the prognosis of patients.https://aammt.tmmu.edu.cn/Upload/rhtml/202011256.htmintracranial aneurysmclippingdelayed cerebral infarctionrisk factors |
| spellingShingle | SU Jun SU Jun HAUNG Hao XIN Yuanjun WU Xintong YANG Xiaolin HE Zhaohui Risk factors for delayed cerebral infarction after intracranial aneurysm clipping Di-san junyi daxue xuebao intracranial aneurysm clipping delayed cerebral infarction risk factors |
| title | Risk factors for delayed cerebral infarction after intracranial aneurysm clipping |
| title_full | Risk factors for delayed cerebral infarction after intracranial aneurysm clipping |
| title_fullStr | Risk factors for delayed cerebral infarction after intracranial aneurysm clipping |
| title_full_unstemmed | Risk factors for delayed cerebral infarction after intracranial aneurysm clipping |
| title_short | Risk factors for delayed cerebral infarction after intracranial aneurysm clipping |
| title_sort | risk factors for delayed cerebral infarction after intracranial aneurysm clipping |
| topic | intracranial aneurysm clipping delayed cerebral infarction risk factors |
| url | https://aammt.tmmu.edu.cn/Upload/rhtml/202011256.htm |
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