Neuronal Lipoprotein Lipase Deficiency Alters Neuronal Function and Hepatic Metabolism

Neuronal Lipoprotein Lipase Deficiency Alters Neuronal Function and Hepatic Metabolism

The autonomic regulation of hepatic metabolism offers a novel target for the treatment of non-alcoholic fatty liver disease (NAFLD). However, the molecular characteristics of neurons that regulate the brain-liver axis remain unclear. Since mice lacking neuronal lipoprotein lipase (LPL) develop pertu...

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Bibliographic Details
Main Authors: Kimberley D. Bruce, Evgenia Dobrinskikh, Hong Wang, Ivan Rudenko, Hong Gao, Andrew E. Libby, Sachi Gorkhali, Tian Yu, Andrea Zsombok, Robert H. Eckel
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Metabolites
Subjects:
lipoprotein lipase
neuronal metabolism
fatty liver
brain-liver axis
FLIM
Online Access:https://www.mdpi.com/2218-1989/10/10/385

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