Ayurveda-modern medicine interface: A critical appraisal of studies of Ayurvedic medicines to treat osteoarthritis and rheumatoid arthritis

The potential of Ayurvedic philosophy and medicines needs to be recognized and converted into real life treatment paradigm. This article describes a comprehensive therapeutic approach used in Ayurveda and modern medicine to treat arthritis. We present concise summary of various controlled drug trial...

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Main Authors: Arvind Chopra, Manjit Saluja, Girish Tillu
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Journal of Ayurveda and Integrative Medicine
Subjects:
Online Access:http://www.jaim.in/article.asp?issn=0975-9476;year=2010;volume=1;issue=3;spage=190;epage=198;aulast=Chopra
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author Arvind Chopra
Manjit Saluja
Girish Tillu
author_facet Arvind Chopra
Manjit Saluja
Girish Tillu
author_sort Arvind Chopra
collection DOAJ
description The potential of Ayurvedic philosophy and medicines needs to be recognized and converted into real life treatment paradigm. This article describes a comprehensive therapeutic approach used in Ayurveda and modern medicine to treat arthritis. We present concise summary of various controlled drug trials carried out by us to validate standardized Ayurvedic drugs using modern medicine protocol to treat Rheumatoid Arthritis and Osteoarthritis knees. Several of the latter are published. The trials consistently demonstrate excellent safety of Ayurvedic medicines but often fail to unequivocally show superior efficacy. Some key findings of a recently unpublished trial in OA knees are also presented to show equivalence between Ayurvedic medicine and celecoxib and glucosamine, and we speculate that equivalence trials may be a way forward. The data from the trials also supports the Ayurvedic ′Rasayana′ concept of immune-modulation and healing. We need to interpret logic of Ayurveda when, adopting modern science tools in drug development and validation and much research is required. Validation of Ayurvedic medicines using the latter approach may lead to an evidence based Ayurveda - Modern Medicine interface. Also, in pursuit of finding better treatment solutions, we ought to step beyond the realm of only drugs and attempt validation of comprehensive specific treatment package as per classical Ayurveda. Finally, validation of a combined (Ayurveda and modern medicine) therapeutic approach with superior efficacy and safety is likely to be a major leap in overcoming some of the current frustrations to treat difficult disorders like arthritis using only modern medicines.
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spelling doaj.art-55ac9ac6eb3c466981653aa311b671bb2022-12-22T01:14:41ZengElsevierJournal of Ayurveda and Integrative Medicine0975-94762010-01-011319019810.4103/0975-9476.72620Ayurveda-modern medicine interface: A critical appraisal of studies of Ayurvedic medicines to treat osteoarthritis and rheumatoid arthritisArvind ChopraManjit SalujaGirish TilluThe potential of Ayurvedic philosophy and medicines needs to be recognized and converted into real life treatment paradigm. This article describes a comprehensive therapeutic approach used in Ayurveda and modern medicine to treat arthritis. We present concise summary of various controlled drug trials carried out by us to validate standardized Ayurvedic drugs using modern medicine protocol to treat Rheumatoid Arthritis and Osteoarthritis knees. Several of the latter are published. The trials consistently demonstrate excellent safety of Ayurvedic medicines but often fail to unequivocally show superior efficacy. Some key findings of a recently unpublished trial in OA knees are also presented to show equivalence between Ayurvedic medicine and celecoxib and glucosamine, and we speculate that equivalence trials may be a way forward. The data from the trials also supports the Ayurvedic ′Rasayana′ concept of immune-modulation and healing. We need to interpret logic of Ayurveda when, adopting modern science tools in drug development and validation and much research is required. Validation of Ayurvedic medicines using the latter approach may lead to an evidence based Ayurveda - Modern Medicine interface. Also, in pursuit of finding better treatment solutions, we ought to step beyond the realm of only drugs and attempt validation of comprehensive specific treatment package as per classical Ayurveda. Finally, validation of a combined (Ayurveda and modern medicine) therapeutic approach with superior efficacy and safety is likely to be a major leap in overcoming some of the current frustrations to treat difficult disorders like arthritis using only modern medicines.http://www.jaim.in/article.asp?issn=0975-9476;year=2010;volume=1;issue=3;spage=190;epage=198;aulast=ChopraAyurvedarheumatoid arthritisosteoarthritisclinical trialsRasayana
spellingShingle Arvind Chopra
Manjit Saluja
Girish Tillu
Ayurveda-modern medicine interface: A critical appraisal of studies of Ayurvedic medicines to treat osteoarthritis and rheumatoid arthritis
Journal of Ayurveda and Integrative Medicine
Ayurveda
rheumatoid arthritis
osteoarthritis
clinical trials
Rasayana
title Ayurveda-modern medicine interface: A critical appraisal of studies of Ayurvedic medicines to treat osteoarthritis and rheumatoid arthritis
title_full Ayurveda-modern medicine interface: A critical appraisal of studies of Ayurvedic medicines to treat osteoarthritis and rheumatoid arthritis
title_fullStr Ayurveda-modern medicine interface: A critical appraisal of studies of Ayurvedic medicines to treat osteoarthritis and rheumatoid arthritis
title_full_unstemmed Ayurveda-modern medicine interface: A critical appraisal of studies of Ayurvedic medicines to treat osteoarthritis and rheumatoid arthritis
title_short Ayurveda-modern medicine interface: A critical appraisal of studies of Ayurvedic medicines to treat osteoarthritis and rheumatoid arthritis
title_sort ayurveda modern medicine interface a critical appraisal of studies of ayurvedic medicines to treat osteoarthritis and rheumatoid arthritis
topic Ayurveda
rheumatoid arthritis
osteoarthritis
clinical trials
Rasayana
url http://www.jaim.in/article.asp?issn=0975-9476;year=2010;volume=1;issue=3;spage=190;epage=198;aulast=Chopra
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AT manjitsaluja ayurvedamodernmedicineinterfaceacriticalappraisalofstudiesofayurvedicmedicinestotreatosteoarthritisandrheumatoidarthritis
AT girishtillu ayurvedamodernmedicineinterfaceacriticalappraisalofstudiesofayurvedicmedicinestotreatosteoarthritisandrheumatoidarthritis