FGF21/FGFR1-β-KL cascade in cardiomyocytes modulates angiogenesis and inflammation under metabolic stress

FGF21/FGFR1-β-KL cascade in cardiomyocytes modulates angiogenesis and inflammation under metabolic stress

Diabetes is a metabolic disorder with an increased risk of developing heart failure. Inflammation and damaged vasculature are the cardinal features of diabetes-induced cardiac damage. Moreover, systemic metabolic stress triggers discordant intercellular communication, thus culminating in cardiac dys...

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Bibliographic Details
Main Authors: Namrita Kaur, Sanskruti Ravindra Gare, Andrea Ruiz-Velasco, Jessica M. Miller, Riham R.E. Abouleisa, Qinghui Ou, Jiahan Shen, Handrean Soran, Tamer M.A. Mohamed, Wei Liu
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Heliyon
Subjects:
Metabolic stress
Intercellular communication
Diabetic cardiomyopathy
Inflammation
Angiogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402302159X

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