Selenium-containing compounds and D-panthetine modulate the action of doxorubicin and cisplatin towards drug-resistant tumor cells

Selenium-containing compounds and D-panthetine modulate the action of doxorubicin and cisplatin towards drug-resistant tumor cells

The aim of this work was to study biological activity of sodium selenite, selenomethionine and D-panthetine towards drug-resistant human leukemia and carcinoma cells, characterized by overexpression of P-glycoprotein and knockout of Bax gene which plays a key role in the induction of cell death. It...

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Bibliographic Details
Main Authors:	R. R. Panchuk, N. R. Skorokhyd, V. V. Chumak, L. V. Lehka, A. G. Moiseenok, W. Berger, R. S. Stoika
Format:	Article
Language:	English
Published:	Львівський національний університет імені Івана Франка 2013-12-01
Series:	Біологічні студії
Subjects:	antioxidants anticancer drugs reactive oxygen species selenomethionine sodium selenite d-panthetine
Online Access:	http://publications.lnu.edu.ua/journals/index.php/biology/article/view/264

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