Maitotoxin Is a Potential Selective Activator of the Endogenous Transient Receptor Potential Canonical Type 1 Channel in Xenopus laevis Oocytes

Maitotoxin Is a Potential Selective Activator of the Endogenous Transient Receptor Potential Canonical Type 1 Channel in Xenopus laevis Oocytes

Maitotoxin (MTX) is the most potent marine toxin known to date. It is responsible for a particular human intoxication syndrome called ciguatera fish poisoning (CFP). Several reports indicate that MTX is an activator of non-selective cation channels (NSCC) in different cell types. The molecular ident...

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Bibliographic Details
Main Authors: Pedro L. Flores, Emma Rodríguez, Estrella Zapata, Roxana Carbó, José María Farías, Martín Martínez
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Marine Drugs
Subjects:
Xenopus laevis oocytes
maitotoxin
ciguatera fish poisoning
TRPC channels
Online Access:http://www.mdpi.com/1660-3397/15/7/198

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