Comprehensive analysis of cis- and trans-acting factors affecting ectopic Break-Induced Replication.

Comprehensive analysis of cis- and trans-acting factors affecting ectopic Break-Induced Replication.

Break-induced replication (BIR) is a highly mutagenic eukaryotic homologous DNA recombination pathway that repairs one-ended DNA double strand breaks such as broken DNA replication forks and eroded telomeres. While searching for cis-acting factors regulating ectopic BIR efficiency, we found that ect...

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Bibliographic Details
Main Authors: Tannia Uribe-Calvillo, Laetitia Maestroni, Marie-Claude Marsolier, Basheer Khadaroo, Christine Arbiol, Jonathan Schott, Bertrand Llorente
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-06-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010124

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