Circulating α-Klotho Levels in Relation to Cardiovascular Diseases: A Mendelian Randomization Study

Circulating α-Klotho Levels in Relation to Cardiovascular Diseases: A Mendelian Randomization Study

BackgroundSeveral studies have reported a protective role of circulating α-Klotho on cardiovascular diseases (CVD); however, the causality remains unclear. We aim to elucidate whether genetically predicted circulating α-Klotho levels were causally associated with the risk of coronary artery disease...

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Bibliographic Details
Main Authors: Xingang Sun, Lu Chen, Yuxian He, Liangrong Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Endocrinology
Subjects:
α-klotho
coronary artery disease
myocardial infarction
atrial fibrillation
heart failure
stroke
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.842846/full

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