Intramedullary Spinal Cord Compression Caused by Histoplasma capsulatum: A Case Report and Meta-Analysis
Abstract Nine cases of intramedullar histoplasmosis have been published in the literature. In six cases, spinal cord compression was associated with brain localization or with contex of disseminated histoplasmosis. The authors are reporting here the third isolated spinal cord compression in immunoco...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Thieme Medical Publishers, Inc.
2015-07-01
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| Series: | Indian Journal of Neurosurgery |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0035-1558837 |
| _version_ | 1818083661904347136 |
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| author | Dominique N'Dri-Oka Nicole Adou André Tokpa Louis Derou |
| author_facet | Dominique N'Dri-Oka Nicole Adou André Tokpa Louis Derou |
| author_sort | Dominique N'Dri-Oka |
| collection | DOAJ |
| description | Abstract
Nine cases of intramedullar histoplasmosis have been published in the literature. In six cases, spinal cord compression was associated with brain localization or with contex of disseminated histoplasmosis. The authors are reporting here the third isolated spinal cord compression in immunocompetent 42-year-old African-rabbits breeder, a woman. This case was successfully managed with surgical removal of the lesion associated to itraconazole during 8 months. Intramedullar lesion because of the Histoplasma capsulatum was necrosis granulomatous localized at spinal conus.
In conclusion, according to literature data the most frequent spinal cord compression caused by histoplasmosis capsulatum. General risk factors include residence in endemic areas as well as immunosuppression. Endemic areas include Africa, Australia, parts of Eastern Asia, and America (Mississippi, Missouri, and Ohio River valleys). Initial localization was cutaneous. Two histopathological forms reported are abscess and necrotizing granuloma. Management is mainly based on antifungus like itraconazole. Surgery is only necessary for the etiology diagnosis. |
| first_indexed | 2024-12-10T19:41:33Z |
| format | Article |
| id | doaj.art-55be7cd780f3429e95b8aaf950b63f27 |
| institution | Directory Open Access Journal |
| issn | 2277-954X 2277-9167 |
| language | English |
| last_indexed | 2024-12-10T19:41:33Z |
| publishDate | 2015-07-01 |
| publisher | Thieme Medical Publishers, Inc. |
| record_format | Article |
| series | Indian Journal of Neurosurgery |
| spelling | doaj.art-55be7cd780f3429e95b8aaf950b63f272022-12-22T01:35:59ZengThieme Medical Publishers, Inc.Indian Journal of Neurosurgery2277-954X2277-91672015-07-01040210911310.1055/s-0035-1558837Intramedullary Spinal Cord Compression Caused by Histoplasma capsulatum: A Case Report and Meta-AnalysisDominique N'Dri-Oka0Nicole Adou1André Tokpa2Louis Derou3Neurosurgery Department at Abidjan Yopougon University Hospital in Ivory Coast, Abidjan, Ivory CoastNeurosurgery Department at Abidjan Yopougon University Hospital in Ivory Coast, Abidjan, Ivory CoastNeurosurgery Department at Abidjan Yopougon University Hospital in Ivory Coast, Abidjan, Ivory CoastNeurosurgery Department at Abidjan Yopougon University Hospital in Ivory Coast, Abidjan, Ivory CoastAbstract Nine cases of intramedullar histoplasmosis have been published in the literature. In six cases, spinal cord compression was associated with brain localization or with contex of disseminated histoplasmosis. The authors are reporting here the third isolated spinal cord compression in immunocompetent 42-year-old African-rabbits breeder, a woman. This case was successfully managed with surgical removal of the lesion associated to itraconazole during 8 months. Intramedullar lesion because of the Histoplasma capsulatum was necrosis granulomatous localized at spinal conus. In conclusion, according to literature data the most frequent spinal cord compression caused by histoplasmosis capsulatum. General risk factors include residence in endemic areas as well as immunosuppression. Endemic areas include Africa, Australia, parts of Eastern Asia, and America (Mississippi, Missouri, and Ohio River valleys). Initial localization was cutaneous. Two histopathological forms reported are abscess and necrotizing granuloma. Management is mainly based on antifungus like itraconazole. Surgery is only necessary for the etiology diagnosis.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0035-1558837 histoplasma capsulatum necrosis granulomaspinal cord lesionmeta-analysis |
| spellingShingle | Dominique N'Dri-Oka Nicole Adou André Tokpa Louis Derou Intramedullary Spinal Cord Compression Caused by Histoplasma capsulatum: A Case Report and Meta-Analysis Indian Journal of Neurosurgery histoplasma capsulatum necrosis granuloma spinal cord lesion meta-analysis |
| title | Intramedullary Spinal Cord Compression Caused by Histoplasma capsulatum: A Case Report and Meta-Analysis |
| title_full | Intramedullary Spinal Cord Compression Caused by Histoplasma capsulatum: A Case Report and Meta-Analysis |
| title_fullStr | Intramedullary Spinal Cord Compression Caused by Histoplasma capsulatum: A Case Report and Meta-Analysis |
| title_full_unstemmed | Intramedullary Spinal Cord Compression Caused by Histoplasma capsulatum: A Case Report and Meta-Analysis |
| title_short | Intramedullary Spinal Cord Compression Caused by Histoplasma capsulatum: A Case Report and Meta-Analysis |
| title_sort | intramedullary spinal cord compression caused by histoplasma capsulatum a case report and meta analysis |
| topic | histoplasma capsulatum necrosis granuloma spinal cord lesion meta-analysis |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0035-1558837 |
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