Genome architecture plasticity underlies DNA replication timing dynamics in cell differentiation
During the S-phase of eukaryotic cell cycle, DNA is replicated in a dedicatedly regulated temporal order, with regions containing active and inactive genes replicated early and late, respectively. Recent advances in sequencing technology allow us to explore the connection between replication timing...
Main Authors: | Wenjun Yu, Quan Zhong, Zi Wen, Weihan Zhang, Yanrong Huang |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-09-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fgene.2022.961612/full |
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