Evaluation of the relationship between left atrial volume and myocardial ischemia: a systematic review
Introduction: The pathophysiology of ischemia involves the cellular effect of myocardial ischemia, reactive oxygen species, and reactive inflammatory enzymes. Left atrial (LA) ischemia has been shown to have several mechanisms through which it can lead to abnormalities in left ventricular filling in...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2017-07-01
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| Series: | Reviews in Clinical Medicine |
| Subjects: | |
| Online Access: | https://rcm.mums.ac.ir/article_6401_e5fa570393d8d4330e27d5433e152a1b.pdf |
| _version_ | 1797976070727663616 |
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| author | Ali Azari leila Bigdelue Afsoon Fazlinezhad Marzye Farazandeh Somaye Bakefayat |
| author_facet | Ali Azari leila Bigdelue Afsoon Fazlinezhad Marzye Farazandeh Somaye Bakefayat |
| author_sort | Ali Azari |
| collection | DOAJ |
| description | Introduction: The pathophysiology of ischemia involves the cellular effect of myocardial ischemia, reactive oxygen species, and reactive inflammatory enzymes. Left atrial (LA) ischemia has been shown to have several mechanisms through which it can lead to abnormalities in left ventricular filling in early diastole and thus reduces LA passive functional reserve. In this review, we evaluated the physiological mechanisms of LA during myocardial ischemia, as previously demonstrated in experimental and clinical studies.Methods: Several databases were searched in order to find related articles. The outcome of interest included LA function measurements (measurement of LA volume) during ischemia. By applying a standardized protocol, reviewers independently extracted and assessed the studies.Results: The literature review indicated 50 publications, among which 15 studies were eligible for analysis. Assessment of LA dimension and function is essential for clinical evaluation and prognostic purposes. Conclusion: The present article revealed that LA passive emptying volume and LA emptying volume significantly increased in myocardial ischemia. Further researches could provide a better understanding of pathophysiological mechanisms behind LA enlargement and help to predict clinical outcomes in many cardiovascular disorders. |
| first_indexed | 2024-04-11T04:45:30Z |
| format | Article |
| id | doaj.art-55c37edbc70f402aafaf10a31c08545f |
| institution | Directory Open Access Journal |
| issn | 2345-6256 2345-6892 |
| language | English |
| last_indexed | 2024-04-11T04:45:30Z |
| publishDate | 2017-07-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Reviews in Clinical Medicine |
| spelling | doaj.art-55c37edbc70f402aafaf10a31c08545f2022-12-27T13:09:25ZengMashhad University of Medical SciencesReviews in Clinical Medicine2345-62562345-68922017-07-01439710110.22038/rcm.2016.64016401Evaluation of the relationship between left atrial volume and myocardial ischemia: a systematic reviewAli Azari0leila Bigdelue1Afsoon Fazlinezhad2Marzye Farazandeh3Somaye Bakefayat4Division of Cardiovascular, Vascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.Division of Cardiovascular, Vascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.Division of Cardiovascular, Vascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.Division of Cardiovascular, Vascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.Division of Cardiovascular, Vascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.Introduction: The pathophysiology of ischemia involves the cellular effect of myocardial ischemia, reactive oxygen species, and reactive inflammatory enzymes. Left atrial (LA) ischemia has been shown to have several mechanisms through which it can lead to abnormalities in left ventricular filling in early diastole and thus reduces LA passive functional reserve. In this review, we evaluated the physiological mechanisms of LA during myocardial ischemia, as previously demonstrated in experimental and clinical studies.Methods: Several databases were searched in order to find related articles. The outcome of interest included LA function measurements (measurement of LA volume) during ischemia. By applying a standardized protocol, reviewers independently extracted and assessed the studies.Results: The literature review indicated 50 publications, among which 15 studies were eligible for analysis. Assessment of LA dimension and function is essential for clinical evaluation and prognostic purposes. Conclusion: The present article revealed that LA passive emptying volume and LA emptying volume significantly increased in myocardial ischemia. Further researches could provide a better understanding of pathophysiological mechanisms behind LA enlargement and help to predict clinical outcomes in many cardiovascular disorders.https://rcm.mums.ac.ir/article_6401_e5fa570393d8d4330e27d5433e152a1b.pdfcardiac volumeleft atrial functionsmyocardial ischemia |
| spellingShingle | Ali Azari leila Bigdelue Afsoon Fazlinezhad Marzye Farazandeh Somaye Bakefayat Evaluation of the relationship between left atrial volume and myocardial ischemia: a systematic review Reviews in Clinical Medicine cardiac volume left atrial functions myocardial ischemia |
| title | Evaluation of the relationship between left atrial volume and myocardial ischemia: a systematic review |
| title_full | Evaluation of the relationship between left atrial volume and myocardial ischemia: a systematic review |
| title_fullStr | Evaluation of the relationship between left atrial volume and myocardial ischemia: a systematic review |
| title_full_unstemmed | Evaluation of the relationship between left atrial volume and myocardial ischemia: a systematic review |
| title_short | Evaluation of the relationship between left atrial volume and myocardial ischemia: a systematic review |
| title_sort | evaluation of the relationship between left atrial volume and myocardial ischemia a systematic review |
| topic | cardiac volume left atrial functions myocardial ischemia |
| url | https://rcm.mums.ac.ir/article_6401_e5fa570393d8d4330e27d5433e152a1b.pdf |
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