Three-Dimensional Culture Model of Skeletal Muscle Tissue with Atrophy Induced by Dexamethasone

Three-Dimensional Culture Model of Skeletal Muscle Tissue with Atrophy Induced by Dexamethasone

Drug screening systems for muscle atrophy based on the contractile force of cultured skeletal muscle tissues are required for the development of preventive or therapeutic drugs for atrophy. This study aims to develop a muscle atrophy model by inducing atrophy in normal muscle tissues constructed on...

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Bibliographic Details
Main Authors: Kazunori Shimizu, Riho Genma, Yuuki Gotou, Sumire Nagasaka, Hiroyuki Honda
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Bioengineering
Subjects:
cell-based assay
disease model
drug screening
contractile force
microdevice
Online Access:http://www.mdpi.com/2306-5354/4/2/56

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