Potential of the Pentacam in Screening for Narrow Angles in Patients with Chronic Angle-Closure Glaucoma
Background: Chronic angle-closure glaucoma (CACG) is a visually destructive disease. Effective management of CACG requires identifying eyes with narrow angle. Objective: To compare pentacam with gonioscopy in detecting narrow angles in eyes with CACG. Method: We enrolled 101 eyes with glaucoma....
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Surgical Society of Kenya
2021-01-01
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| Series: | The Annals of African Surgery |
| Subjects: | |
| Online Access: | https://www.annalsofafricansurgery.com/pentacam-closure-glaucoma |
| _version_ | 1818864875993038848 |
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| author | Seth Lartey Abdul-Kabir Mohammed Emmanuel Appiagyei Kojo Akuffo |
| author_facet | Seth Lartey Abdul-Kabir Mohammed Emmanuel Appiagyei Kojo Akuffo |
| author_sort | Seth Lartey |
| collection | DOAJ |
| description | Background: Chronic angle-closure glaucoma (CACG)
is a visually destructive disease. Effective management
of CACG requires identifying eyes with narrow angle.
Objective: To compare pentacam with gonioscopy in
detecting narrow angles in eyes with CACG. Method:
We enrolled 101 eyes with glaucoma. Gonioscopy was
performed on all eyes. Using Shaffer’s grading, subjects
were classified into angle closure and open angle.
Anterior chamber volume (ACV) and anterior chamber
depth (ACD) were measured with the pentacam.
Receiver operating curve was constructed for each
parameter and the area under the curve (AUC) was
calculated. Results: Ten eyes (9.9%) were classified as
angle closure on gonioscopy. To detect narrow angles,
ACV (AUC 0.956; 95% confidence interval (CI) 0.894–
0.987) performed similar to ACD (AUC=0.930,
p=0.33). Using a cutoff of 102 mm3, ACV had 100%
sensitivity and 88.5% specificity for detecting narrow
angles in CACG patients. With an ACV cutoff of 102
mm3, the PPV for detecting angle closure was 48.9%
(95% CI, 34.8–68.2), while the NPV was 100% (94.1–
100%), using 9.9% prevalence of angle closure from this
study. Conclusion: ACV and ACD measured by the
pentacam have the potential to determine narrow angles
in eyes with CACG. |
| first_indexed | 2024-12-19T10:38:37Z |
| format | Article |
| id | doaj.art-55ccb0437ffa4602982a4341cc03641b |
| institution | Directory Open Access Journal |
| issn | 1999-9674 2523-0816 |
| language | English |
| last_indexed | 2024-12-19T10:38:37Z |
| publishDate | 2021-01-01 |
| publisher | Surgical Society of Kenya |
| record_format | Article |
| series | The Annals of African Surgery |
| spelling | doaj.art-55ccb0437ffa4602982a4341cc03641b2022-12-21T20:25:32ZengSurgical Society of KenyaThe Annals of African Surgery1999-96742523-08162021-01-011813944Potential of the Pentacam in Screening for Narrow Angles in Patients with Chronic Angle-Closure GlaucomaSeth Lartey0Abdul-Kabir Mohammed1Emmanuel Appiagyei2Kojo Akuffo3EENT Department, Kwame Nkrumah University of Science and TechnologyDepartment of Optometry, Kwame Nkrumah University of Science and TechnologyEye Department, Komfo Anokye Teaching HospitalDepartment of Optometry, Kwame Nkrumah University of Science and TechnologyBackground: Chronic angle-closure glaucoma (CACG) is a visually destructive disease. Effective management of CACG requires identifying eyes with narrow angle. Objective: To compare pentacam with gonioscopy in detecting narrow angles in eyes with CACG. Method: We enrolled 101 eyes with glaucoma. Gonioscopy was performed on all eyes. Using Shaffer’s grading, subjects were classified into angle closure and open angle. Anterior chamber volume (ACV) and anterior chamber depth (ACD) were measured with the pentacam. Receiver operating curve was constructed for each parameter and the area under the curve (AUC) was calculated. Results: Ten eyes (9.9%) were classified as angle closure on gonioscopy. To detect narrow angles, ACV (AUC 0.956; 95% confidence interval (CI) 0.894– 0.987) performed similar to ACD (AUC=0.930, p=0.33). Using a cutoff of 102 mm3, ACV had 100% sensitivity and 88.5% specificity for detecting narrow angles in CACG patients. With an ACV cutoff of 102 mm3, the PPV for detecting angle closure was 48.9% (95% CI, 34.8–68.2), while the NPV was 100% (94.1– 100%), using 9.9% prevalence of angle closure from this study. Conclusion: ACV and ACD measured by the pentacam have the potential to determine narrow angles in eyes with CACG.https://www.annalsofafricansurgery.com/pentacam-closure-glaucomachronic angle-closure glaucomapentacam hranterior chamber volumegonioscopy |
| spellingShingle | Seth Lartey Abdul-Kabir Mohammed Emmanuel Appiagyei Kojo Akuffo Potential of the Pentacam in Screening for Narrow Angles in Patients with Chronic Angle-Closure Glaucoma The Annals of African Surgery chronic angle-closure glaucoma pentacam hr anterior chamber volume gonioscopy |
| title | Potential of the Pentacam in Screening for Narrow Angles in Patients with Chronic Angle-Closure Glaucoma |
| title_full | Potential of the Pentacam in Screening for Narrow Angles in Patients with Chronic Angle-Closure Glaucoma |
| title_fullStr | Potential of the Pentacam in Screening for Narrow Angles in Patients with Chronic Angle-Closure Glaucoma |
| title_full_unstemmed | Potential of the Pentacam in Screening for Narrow Angles in Patients with Chronic Angle-Closure Glaucoma |
| title_short | Potential of the Pentacam in Screening for Narrow Angles in Patients with Chronic Angle-Closure Glaucoma |
| title_sort | potential of the pentacam in screening for narrow angles in patients with chronic angle closure glaucoma |
| topic | chronic angle-closure glaucoma pentacam hr anterior chamber volume gonioscopy |
| url | https://www.annalsofafricansurgery.com/pentacam-closure-glaucoma |
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