Temporal Dynamics of Diffusion Metrics in Early Multiple Sclerosis and Clinically Isolated Syndrome: A 2-Year Follow-Up Tract-Based Spatial Statistics Study

Temporal Dynamics of Diffusion Metrics in Early Multiple Sclerosis and Clinically Isolated Syndrome: A 2-Year Follow-Up Tract-Based Spatial Statistics Study

Background: Tract-based spatial statistics (TBSS) is suitable for the assessment of voxel-wise changes in fiber integrity in WM tracts in the entire brain. Longitudinal TBSS analyses of early multiple sclerosis (MS) using 3 Tesla magnetic resonance imaging (MRI) are not common.Objective: To characte...

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Bibliographic Details
Main Authors: Ruth Schneider, Erhan Genç, Christian Ahlborn, Ralf Gold, Carsten Lukas, Barbara Bellenberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Neurology
Subjects:
multiple sclerosis (MS)
clinically isolated syndrome (CIS)
diffusion tensor imaging (DTI)
tract-based spatial statistics (TBSS)
fractional anisotropy (FA)
radial diffusivity (RD)
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.01165/full

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