Adenoviral transduction of mesenchymal stem cells: in vitro responses and in vivo immune responses after cell transplantation.

Adenoviral transduction of mesenchymal stem cells: in vitro responses and in vivo immune responses after cell transplantation.

Adult mesenchymal stem cells (MSCs) are non-hematopoietic cells with multi-lineage potential which makes them attractive targets for regenerative medicine applications. However, to date, therapeutic success of MSC-therapy is limited and the genetic modification of MSCs using viral vectors is one opt...

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Bibliographic Details
Main Authors: Oliver Treacy, Aideen E Ryan, Teresa Heinzl, Lisa O'Flynn, Marese Cregg, Mieszko Wilk, Francesca Odoardi, Paul Lohan, Timothy O'Brien, Mikhail Nosov, Thomas Ritter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22880073/?tool=EBI

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