Intrapleural urokinase directly under medical thoracoscopy for the diagnosis of tuberculous pleurisy

Medical thoracoscopy, also called “local anesthetic thoracoscopy” and “pleuroscopy,” is a minimally invasive single‐port endoscopic technique that provides direct visualization of the pleural surfaces and channels to conduct diagnostic and therapeutic procedures. However, this technique is not helpf...

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Main Authors: Satoshi Terashita, Hiroaki Kawachi, Tomoko Tajiri, Susumu Noguchi, Tatsuyoshi Ikeue, Takakazu Sugita
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Respirology Case Reports
Subjects:
Online Access:https://doi.org/10.1002/rcr2.498
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author Satoshi Terashita
Hiroaki Kawachi
Tomoko Tajiri
Susumu Noguchi
Tatsuyoshi Ikeue
Takakazu Sugita
author_facet Satoshi Terashita
Hiroaki Kawachi
Tomoko Tajiri
Susumu Noguchi
Tatsuyoshi Ikeue
Takakazu Sugita
author_sort Satoshi Terashita
collection DOAJ
description Medical thoracoscopy, also called “local anesthetic thoracoscopy” and “pleuroscopy,” is a minimally invasive single‐port endoscopic technique that provides direct visualization of the pleural surfaces and channels to conduct diagnostic and therapeutic procedures. However, this technique is not helpful when substantial fibrous adhesions exist. We reported the first case of intrapleural urokinase directly under medical thoracoscopy for the diagnosis of malignant pleural mesothelioma with severe multiloculated pleural effusions in 2019. This is the second report regarding the efficacy of intrapleural urokinase directly under medical thoracoscopy for the diagnosis of multiloculated pleural effusions. Urokinase‐induced intrapleural fibrinolysis, which removed the fibrous septa, consequently improved the field of view under endoscopy within only 10 min. Fibrinolytic effect appeared very rapidly. This technique is available for tuberculous pleurisy with severe multiloculated pleural effusion.
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spelling doaj.art-55d6ace05f9a4de8862316d9e0ca86852022-12-21T18:15:32ZengWileyRespirology Case Reports2051-33802020-01-0181n/an/a10.1002/rcr2.498Intrapleural urokinase directly under medical thoracoscopy for the diagnosis of tuberculous pleurisySatoshi Terashita0Hiroaki Kawachi1Tomoko Tajiri2Susumu Noguchi3Tatsuyoshi Ikeue4Takakazu Sugita5Department of Respiratory Medicine Japanese Red Cross Wakayama Medical Center Wakayama JapanDepartment of Respiratory Medicine Japanese Red Cross Wakayama Medical Center Wakayama JapanDepartment of Respiratory Medicine Japanese Red Cross Wakayama Medical Center Wakayama JapanDepartment of Respiratory Medicine Japanese Red Cross Wakayama Medical Center Wakayama JapanDepartment of Respiratory Medicine Japanese Red Cross Wakayama Medical Center Wakayama JapanDepartment of Respiratory Medicine Japanese Red Cross Wakayama Medical Center Wakayama JapanMedical thoracoscopy, also called “local anesthetic thoracoscopy” and “pleuroscopy,” is a minimally invasive single‐port endoscopic technique that provides direct visualization of the pleural surfaces and channels to conduct diagnostic and therapeutic procedures. However, this technique is not helpful when substantial fibrous adhesions exist. We reported the first case of intrapleural urokinase directly under medical thoracoscopy for the diagnosis of malignant pleural mesothelioma with severe multiloculated pleural effusions in 2019. This is the second report regarding the efficacy of intrapleural urokinase directly under medical thoracoscopy for the diagnosis of multiloculated pleural effusions. Urokinase‐induced intrapleural fibrinolysis, which removed the fibrous septa, consequently improved the field of view under endoscopy within only 10 min. Fibrinolytic effect appeared very rapidly. This technique is available for tuberculous pleurisy with severe multiloculated pleural effusion.https://doi.org/10.1002/rcr2.498Intrapleural fibrinolysismedical thoracoscopypleural effusionstuberculous pleurisyurokinase
spellingShingle Satoshi Terashita
Hiroaki Kawachi
Tomoko Tajiri
Susumu Noguchi
Tatsuyoshi Ikeue
Takakazu Sugita
Intrapleural urokinase directly under medical thoracoscopy for the diagnosis of tuberculous pleurisy
Respirology Case Reports
Intrapleural fibrinolysis
medical thoracoscopy
pleural effusions
tuberculous pleurisy
urokinase
title Intrapleural urokinase directly under medical thoracoscopy for the diagnosis of tuberculous pleurisy
title_full Intrapleural urokinase directly under medical thoracoscopy for the diagnosis of tuberculous pleurisy
title_fullStr Intrapleural urokinase directly under medical thoracoscopy for the diagnosis of tuberculous pleurisy
title_full_unstemmed Intrapleural urokinase directly under medical thoracoscopy for the diagnosis of tuberculous pleurisy
title_short Intrapleural urokinase directly under medical thoracoscopy for the diagnosis of tuberculous pleurisy
title_sort intrapleural urokinase directly under medical thoracoscopy for the diagnosis of tuberculous pleurisy
topic Intrapleural fibrinolysis
medical thoracoscopy
pleural effusions
tuberculous pleurisy
urokinase
url https://doi.org/10.1002/rcr2.498
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