Radiofrequency ablation for thyroid Bethesda III nodules: preliminary results
Purpose: The purpose of this study was to evaluate the feasibility of radiofrequency ablation (RFA) for thyroid nodules with cytological atypia of undetermined significance or follicular lesion of undetermined significance (AUS/FLUS, Bethesda III). Materials and methods: A total of 28 adults prese...
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| Format: | Article |
| Language: | English |
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Bioscientifica
2023-10-01
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| Series: | European Thyroid Journal |
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| Online Access: | https://etj.bioscientifica.com/view/journals/etj/12/6/ETJ-23-0105.xml |
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| author | Pi-Ling Chiang Sheng-Dean Luo Yen-Hsiang Chang Chen-Kai Chou Shun-Yu Chi Yi-Fan Chen Wei-Che Lin |
| author_facet | Pi-Ling Chiang Sheng-Dean Luo Yen-Hsiang Chang Chen-Kai Chou Shun-Yu Chi Yi-Fan Chen Wei-Che Lin |
| author_sort | Pi-Ling Chiang |
| collection | DOAJ |
| description | Purpose: The purpose of this study was to evaluate the feasibility of radiofrequency ablation (RFA) for thyroid nodules with cytological atypia of undetermined significance or follicular lesion of undetermined significance (AUS/FLUS, Bethesda III).
Materials and methods: A total of 28 adults presenting with 30 initial Bethesda III nodules underwent thyroid RFA at a single medical center. Thyroid nodules with Bethesda IV or V according to the second aspiration were excluded. All RFA procedures were performed using the free-hand, ‘moving-shot’ technique under local anesthesia. Clinical features and demographics, RFA details, nodule volume reduction rate (VR R), and complications were analyzed.
Results: The mean age of patients was 47.6 years, 82.1% of whom were females. Mean nodule volumes at pre-RFA, and at 6 months and 12 months post-R FA were 7.92, 2.42, and 1.25 mL, respectively, with a VRR of 77.9% at 6 months, and 87.4% at 12 months. Post-RFA complications were noted in two patients, one with transient vocal cord palsy and another with isthmus minor rupture.
Conclusion: RFA may be another safe alternative except for active surveillance or surgical excision for AUS/FLUS nodules with low-suspicion Thyroid Imagin g Reporting and Data System features for patients who are unsuitable or strongly ref use surgery. Long-term results remain uncertain, thus further follow-up study is necessary. |
| first_indexed | 2024-03-11T18:13:06Z |
| format | Article |
| id | doaj.art-55d6c271ea8b4505b23977151bae81bd |
| institution | Directory Open Access Journal |
| issn | 2235-0802 |
| language | English |
| last_indexed | 2024-03-11T18:13:06Z |
| publishDate | 2023-10-01 |
| publisher | Bioscientifica |
| record_format | Article |
| series | European Thyroid Journal |
| spelling | doaj.art-55d6c271ea8b4505b23977151bae81bd2023-10-16T10:07:18ZengBioscientificaEuropean Thyroid Journal2235-08022023-10-0112617https://doi.org/10.1530/ETJ-23-0105Radiofrequency ablation for thyroid Bethesda III nodules: preliminary resultsPi-Ling Chiang0Sheng-Dean Luo1Yen-Hsiang Chang2Chen-Kai Chou3Shun-Yu Chi4Yi-Fan Chen5Wei-Che Lin6Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan; Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan; Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan; Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan; Departments of Surgery, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Thyroid Head and Neck Ablation Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan; Department of Radiology, Jen-Ai Hospital, Dali Branch, Taichung, Taiwan; School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung City, Taiwan Purpose: The purpose of this study was to evaluate the feasibility of radiofrequency ablation (RFA) for thyroid nodules with cytological atypia of undetermined significance or follicular lesion of undetermined significance (AUS/FLUS, Bethesda III). Materials and methods: A total of 28 adults presenting with 30 initial Bethesda III nodules underwent thyroid RFA at a single medical center. Thyroid nodules with Bethesda IV or V according to the second aspiration were excluded. All RFA procedures were performed using the free-hand, ‘moving-shot’ technique under local anesthesia. Clinical features and demographics, RFA details, nodule volume reduction rate (VR R), and complications were analyzed. Results: The mean age of patients was 47.6 years, 82.1% of whom were females. Mean nodule volumes at pre-RFA, and at 6 months and 12 months post-R FA were 7.92, 2.42, and 1.25 mL, respectively, with a VRR of 77.9% at 6 months, and 87.4% at 12 months. Post-RFA complications were noted in two patients, one with transient vocal cord palsy and another with isthmus minor rupture. Conclusion: RFA may be another safe alternative except for active surveillance or surgical excision for AUS/FLUS nodules with low-suspicion Thyroid Imagin g Reporting and Data System features for patients who are unsuitable or strongly ref use surgery. Long-term results remain uncertain, thus further follow-up study is necessary.https://etj.bioscientifica.com/view/journals/etj/12/6/ETJ-23-0105.xmlthyroid nodulebethesda iiiradiofrequency ablationacr ti-rads |
| spellingShingle | Pi-Ling Chiang Sheng-Dean Luo Yen-Hsiang Chang Chen-Kai Chou Shun-Yu Chi Yi-Fan Chen Wei-Che Lin Radiofrequency ablation for thyroid Bethesda III nodules: preliminary results European Thyroid Journal thyroid nodule bethesda iii radiofrequency ablation acr ti-rads |
| title | Radiofrequency ablation for thyroid Bethesda III nodules: preliminary results |
| title_full | Radiofrequency ablation for thyroid Bethesda III nodules: preliminary results |
| title_fullStr | Radiofrequency ablation for thyroid Bethesda III nodules: preliminary results |
| title_full_unstemmed | Radiofrequency ablation for thyroid Bethesda III nodules: preliminary results |
| title_short | Radiofrequency ablation for thyroid Bethesda III nodules: preliminary results |
| title_sort | radiofrequency ablation for thyroid bethesda iii nodules preliminary results |
| topic | thyroid nodule bethesda iii radiofrequency ablation acr ti-rads |
| url | https://etj.bioscientifica.com/view/journals/etj/12/6/ETJ-23-0105.xml |
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