Intestinal Permeability and Circulating CD161+CCR6+CD8+T Cells in Patients With Relapsing–Remitting Multiple Sclerosis Treated With Dimethylfumarate

Intestinal Permeability and Circulating CD161+CCR6+CD8+T Cells in Patients With Relapsing–Remitting Multiple Sclerosis Treated With Dimethylfumarate

Background: The changes of the gut-brain axis have been recently recognized as important components in multiple sclerosis (MS) pathogenesis.Objectives: To evaluate the effects of DMF on intestinal barrier permeability and mucosal immune responses.Methods: We investigated intestinal permeability (IP)...

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Bibliographic Details
Main Authors: Maria C. Buscarinu, Francesca Gargano, Luana Lionetto, Matilde Capi, Emanuele Morena, Arianna Fornasiero, Roberta Reniè, Anna C. Landi, Giulia Pellicciari, Carmela Romano, Rosella Mechelli, Silvia Romano, Giovanna Borsellino, Luca Battistini, Maurizio Simmaco, Corrado Fagnani, Marco Salvetti, Giovanni Ristori
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Neurology
Subjects:
multiple sclerosis
intestinal permeability
CD161+CCR6+CD8+T cells
mucosal immunity
dimethyl-fumarate
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.683398/full

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https://www.frontiersin.org/articles/10.3389/fneur.2021.683398/full

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