Acceptability of cannabidiol in patients with psychosis

Background: Cannabidiol (CBD) is a promising novel candidate treatment for psychosis. It has a more benign side effect profile than antipsychotic medications, and being treated with CBD is not perceived as being stigmatising. These observations suggest that patients with psychosis would find CBD to...

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Main Authors: Edward Chesney, Doga Lamper, Millie Lloyd, Dominic Oliver, Emily Hird, Philip McGuire
Format: Article
Language:English
Published: SAGE Publishing 2022-10-01
Series:Therapeutic Advances in Psychopharmacology
Online Access:https://doi.org/10.1177/20451253221128445
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author Edward Chesney
Doga Lamper
Millie Lloyd
Dominic Oliver
Emily Hird
Philip McGuire
author_facet Edward Chesney
Doga Lamper
Millie Lloyd
Dominic Oliver
Emily Hird
Philip McGuire
author_sort Edward Chesney
collection DOAJ
description Background: Cannabidiol (CBD) is a promising novel candidate treatment for psychosis. It has a more benign side effect profile than antipsychotic medications, and being treated with CBD is not perceived as being stigmatising. These observations suggest that patients with psychosis would find CBD to be a relatively acceptable treatment. Objective: This study tested the above hypothesis by assessing the views of a sample of patients. Methods: Patients with a psychotic disorder were invited to complete a survey exploring their expectations about the efficacy and side effects of CBD. Results: Seventy patients completed the survey. The majority (86%) were willing to try CBD as a treatment. Most patients believed that CBD would improve their psychotic symptoms (69%) and that it would have fewer side effects than their current medication (64%; mainly antipsychotics). A minority of patients (10%) were concerned that CBD might exacerbate their psychotic symptoms. This, however, appeared to reflect confusion between the effects of CBD and those of cannabis. Conclusion: Most patients with psychosis regard CBD as an acceptable treatment. Although CBD has not yet been approved as a treatment for psychosis, many patients are aware of it through the presence of CBD in cannabis and in health supplements. When added to the emerging evidence of its efficacy and the low risk of side effects, the high acceptability of CBD underlines its therapeutic potential.
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spelling doaj.art-55daa9df985d404ea8bd78db752a0aa62022-12-22T04:08:21ZengSAGE PublishingTherapeutic Advances in Psychopharmacology2045-12612022-10-011210.1177/20451253221128445Acceptability of cannabidiol in patients with psychosisEdward ChesneyDoga LamperMillie LloydDominic OliverEmily HirdPhilip McGuireBackground: Cannabidiol (CBD) is a promising novel candidate treatment for psychosis. It has a more benign side effect profile than antipsychotic medications, and being treated with CBD is not perceived as being stigmatising. These observations suggest that patients with psychosis would find CBD to be a relatively acceptable treatment. Objective: This study tested the above hypothesis by assessing the views of a sample of patients. Methods: Patients with a psychotic disorder were invited to complete a survey exploring their expectations about the efficacy and side effects of CBD. Results: Seventy patients completed the survey. The majority (86%) were willing to try CBD as a treatment. Most patients believed that CBD would improve their psychotic symptoms (69%) and that it would have fewer side effects than their current medication (64%; mainly antipsychotics). A minority of patients (10%) were concerned that CBD might exacerbate their psychotic symptoms. This, however, appeared to reflect confusion between the effects of CBD and those of cannabis. Conclusion: Most patients with psychosis regard CBD as an acceptable treatment. Although CBD has not yet been approved as a treatment for psychosis, many patients are aware of it through the presence of CBD in cannabis and in health supplements. When added to the emerging evidence of its efficacy and the low risk of side effects, the high acceptability of CBD underlines its therapeutic potential.https://doi.org/10.1177/20451253221128445
spellingShingle Edward Chesney
Doga Lamper
Millie Lloyd
Dominic Oliver
Emily Hird
Philip McGuire
Acceptability of cannabidiol in patients with psychosis
Therapeutic Advances in Psychopharmacology
title Acceptability of cannabidiol in patients with psychosis
title_full Acceptability of cannabidiol in patients with psychosis
title_fullStr Acceptability of cannabidiol in patients with psychosis
title_full_unstemmed Acceptability of cannabidiol in patients with psychosis
title_short Acceptability of cannabidiol in patients with psychosis
title_sort acceptability of cannabidiol in patients with psychosis
url https://doi.org/10.1177/20451253221128445
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