The Presence of Aflatoxin B1 and Fungi in Traditional Drugs in Vietnam
To explore the presence of aflatoxin B1 (AFB1) and fungi in traditional drugs collected in Vietnam. Materials and Methods: 505 samples of 88 different traditional drugs were obtained from 10 hospitals in Nghe An, a central province of Vietnam. AFB1 contamination was determined by a high-performance...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2022-04-01
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| Series: | Acta Medica Iranica |
| Subjects: | |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/8906 |
| _version_ | 1818126906300563456 |
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| author | Hai Xuan Tang Loi Ba Cao Hoan Huy Dau Tran Anh Le |
| author_facet | Hai Xuan Tang Loi Ba Cao Hoan Huy Dau Tran Anh Le |
| author_sort | Hai Xuan Tang |
| collection | DOAJ |
| description |
To explore the presence of aflatoxin B1 (AFB1) and fungi in traditional drugs collected in Vietnam. Materials and Methods: 505 samples of 88 different traditional drugs were obtained from 10 hospitals in Nghe An, a central province of Vietnam. AFB1 contamination was determined by a high-performance liquid chromatography (HPLC) assay. Fungal contaminants were determined according to WHO regulations and the obtained Aspergillus strains were characterized via morphological and molecular identification. Results: 24 samples (4.75% of the total samples) were contaminated with AFB1 and the average concentration was 0.062± 0.030 µg/kg (ranging from 0.009 to 0.097 µg/kg). Fungal isolates were detected from 174 samples (34.45%). The genus Aspergillus was predominant (82.76% of the isolates) but Rhizopus, Alternaria, Corynespora and yeast were also found in a few samples. Among 144 strains of Aspergillus recovered, A. niger (105 strains) was most frequently found, followed by A. tubingensis (31 strains), A. oryzae (4 strains) and A. flavus (4 strains). Conclusion: This study suggests a low risk of aflatoxin B1 exposure to consumers of traditional drugs in Vietnam.
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| first_indexed | 2024-12-11T07:08:54Z |
| format | Article |
| id | doaj.art-55dd466e3b28443f882f5cf28c3a3001 |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-12-11T07:08:54Z |
| publishDate | 2022-04-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-55dd466e3b28443f882f5cf28c3a30012022-12-22T01:16:25ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942022-04-0160410.18502/acta.v60i4.9268The Presence of Aflatoxin B1 and Fungi in Traditional Drugs in VietnamHai Xuan Tang0Loi Ba Cao1Hoan Huy Dau2Tran Anh Le3Department of Otorhinolaryngology, Nghe An Obstetrics and Pediatrics Hospital, Nghe An, VietnamDepartment of Scientific and Training Management, National Institute of Malariology, Parasitology, and Entomology, Ha Noi, VietnamDepartment of Nghe An Health, Vinh, Nghe An, Vietnam.Department of Parasitology, Vietnam Military Medical University, Ha Noi, Vietnam. To explore the presence of aflatoxin B1 (AFB1) and fungi in traditional drugs collected in Vietnam. Materials and Methods: 505 samples of 88 different traditional drugs were obtained from 10 hospitals in Nghe An, a central province of Vietnam. AFB1 contamination was determined by a high-performance liquid chromatography (HPLC) assay. Fungal contaminants were determined according to WHO regulations and the obtained Aspergillus strains were characterized via morphological and molecular identification. Results: 24 samples (4.75% of the total samples) were contaminated with AFB1 and the average concentration was 0.062± 0.030 µg/kg (ranging from 0.009 to 0.097 µg/kg). Fungal isolates were detected from 174 samples (34.45%). The genus Aspergillus was predominant (82.76% of the isolates) but Rhizopus, Alternaria, Corynespora and yeast were also found in a few samples. Among 144 strains of Aspergillus recovered, A. niger (105 strains) was most frequently found, followed by A. tubingensis (31 strains), A. oryzae (4 strains) and A. flavus (4 strains). Conclusion: This study suggests a low risk of aflatoxin B1 exposure to consumers of traditional drugs in Vietnam. https://acta.tums.ac.ir/index.php/acta/article/view/8906Traditional drugMycotoxinAflatoxinFungiAspergillusVietnam. |
| spellingShingle | Hai Xuan Tang Loi Ba Cao Hoan Huy Dau Tran Anh Le The Presence of Aflatoxin B1 and Fungi in Traditional Drugs in Vietnam Acta Medica Iranica Traditional drug Mycotoxin Aflatoxin Fungi Aspergillus Vietnam. |
| title | The Presence of Aflatoxin B1 and Fungi in Traditional Drugs in Vietnam |
| title_full | The Presence of Aflatoxin B1 and Fungi in Traditional Drugs in Vietnam |
| title_fullStr | The Presence of Aflatoxin B1 and Fungi in Traditional Drugs in Vietnam |
| title_full_unstemmed | The Presence of Aflatoxin B1 and Fungi in Traditional Drugs in Vietnam |
| title_short | The Presence of Aflatoxin B1 and Fungi in Traditional Drugs in Vietnam |
| title_sort | presence of aflatoxin b1 and fungi in traditional drugs in vietnam |
| topic | Traditional drug Mycotoxin Aflatoxin Fungi Aspergillus Vietnam. |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/8906 |
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