Streptococcus suis 2 Transcriptional Regulator TstS Stimulates Cytokine Production and Bacteremia to Promote Streptococcal Toxic Shock-Like Syndrome

Streptococcus suis 2 Transcriptional Regulator TstS Stimulates Cytokine Production and Bacteremia to Promote Streptococcal Toxic Shock-Like Syndrome

Two large-scale outbreaks of streptococcal toxic shock-like syndrome (STSLS) have revealed Streptococcus suis 2 to be a severe and evolving human pathogen. We investigated the mechanism by which S. suis 2 causes STSLS. The transcript abundance of the transcriptional regulator gene tstS was found to...

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Bibliographic Details
Main Authors: Zhongmin Xu, Bo Chen, Qiang Zhang, Liang Liu, Anding Zhang, Yujie Yang, Kaisong Huang, Shuxian Yan, Junping Yu, Xiaomei Sun, Meilin Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Microbiology
Subjects:
Streptococcus suis
transcriptional regulator
STSLS
bacteremia
excessive inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01309/full

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