Cell-free osteoarthritis treatment with dual-engineered chondrocyte-targeted extracellular vesicles derived from mechanical loading primed mesenchymal stem cells

Osteoarthritis (OA) is an age-related chronic inflammatory disease, predominantly characterized by chondrocyte senescence and extracellular matrix (ECM) degradation. Although mesenchymal stem cells (MSCs) derived extracellular vesicles (EVs) are promising for promoting cartilage regeneration, their...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Peng Wang, Haiyue Zhao, Wei Chen, Yuhui Guo, Shuo Zhang, Xin Xing, Shuai Yang, Fengkun Wang, Juan Wang, Zengwu Shao, Yingze Zhang
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: SAGE Publishing 2025-02-01
Cyfres:Journal of Tissue Engineering
Mynediad Ar-lein:https://doi.org/10.1177/20417314241312563