Evaluation of Protein Adsorption and Osseointegration Potential of Polyetheretherketone versus Titanium Dental Implants: A Systematic Review
Introduction: The success of implant therapy depends on a number of parameters, including bone volume implant shape, surface topography, the patient’s overall health, and local factors. Despite the fact that polyetheretherketone (PEEK) implants have undergone a lot of alterations, only a small n...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2023-10-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://www.jcdr.net/articles/PDF/18557/66902_CE[Ra1]_F(SS)_PF1(KB_OM)_PFA(KB_KM)_PN(KM).pdf |
| Summary: | Introduction: The success of implant therapy depends on a
number of parameters, including bone volume implant shape,
surface topography, the patient’s overall health, and local factors.
Despite the fact that polyetheretherketone (PEEK) implants have
undergone a lot of alterations, only a small number of studies
have examined the bioactivity and osseointegration of PEEK
implants with titanium.
Aim: To summarise and evaluate protein adsorption and
osseointegration capacity of PEEK and titanium dental implants.
Materials and Methods: Preferred Reporting Items for
Systematic Reviews and Meta-Analysis (PRISMA) guidelines
were used and PROSPERO (CRD42023415494) registration
was done. Electronic databases were searched for studies
assessing the outcome in terms of protein adsorption and
osseointegration capacity of PEEK and titanium dental implants.
Quality assessment of included studies was evaluated using the
Newcastle-Ottawa Scale (NOS).
Results: Depending on inclusion and exclusion criteria, seven
studies fulfilled the eligibility criteria and were included in
qualitative synthesis. Risk of bias assessment revealed that all
the included studies were largely comparable in methodological
quality. All the included studies had moderate to low-risk of bias
with all the respective domains. All the included studies revealed
that PEEK with optimal surface roughness might hold great
potential for protein adsorption and osseointegration capacity.
Conclusion: Within the limitations of the study, it was found
that compared to titanium, PEEK is less osseoconductive and
bioactive. PEEK is therefore unsuitable for use as a dental
implant in its unmodified form. Implantitis and implant failure
occurs from improper osseoconductivity and bioactivity of
dental implants. |
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| ISSN: | 2249-782X 0973-709X |