Evaluation of Protein Adsorption and Osseointegration Potential of Polyetheretherketone versus Titanium Dental Implants: A Systematic Review
Introduction: The success of implant therapy depends on a number of parameters, including bone volume implant shape, surface topography, the patient’s overall health, and local factors. Despite the fact that polyetheretherketone (PEEK) implants have undergone a lot of alterations, only a small n...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2023-10-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://www.jcdr.net/articles/PDF/18557/66902_CE[Ra1]_F(SS)_PF1(KB_OM)_PFA(KB_KM)_PN(KM).pdf |
| _version_ | 1797649152369229824 |
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| author | Seema Patil Paresh Gandhi Aditi Kanitkar Rupali Patil Bhagyashree Kalsekar |
| author_facet | Seema Patil Paresh Gandhi Aditi Kanitkar Rupali Patil Bhagyashree Kalsekar |
| author_sort | Seema Patil |
| collection | DOAJ |
| description | Introduction: The success of implant therapy depends on a
number of parameters, including bone volume implant shape,
surface topography, the patient’s overall health, and local factors.
Despite the fact that polyetheretherketone (PEEK) implants have
undergone a lot of alterations, only a small number of studies
have examined the bioactivity and osseointegration of PEEK
implants with titanium.
Aim: To summarise and evaluate protein adsorption and
osseointegration capacity of PEEK and titanium dental implants.
Materials and Methods: Preferred Reporting Items for
Systematic Reviews and Meta-Analysis (PRISMA) guidelines
were used and PROSPERO (CRD42023415494) registration
was done. Electronic databases were searched for studies
assessing the outcome in terms of protein adsorption and
osseointegration capacity of PEEK and titanium dental implants.
Quality assessment of included studies was evaluated using the
Newcastle-Ottawa Scale (NOS).
Results: Depending on inclusion and exclusion criteria, seven
studies fulfilled the eligibility criteria and were included in
qualitative synthesis. Risk of bias assessment revealed that all
the included studies were largely comparable in methodological
quality. All the included studies had moderate to low-risk of bias
with all the respective domains. All the included studies revealed
that PEEK with optimal surface roughness might hold great
potential for protein adsorption and osseointegration capacity.
Conclusion: Within the limitations of the study, it was found
that compared to titanium, PEEK is less osseoconductive and
bioactive. PEEK is therefore unsuitable for use as a dental
implant in its unmodified form. Implantitis and implant failure
occurs from improper osseoconductivity and bioactivity of
dental implants. |
| first_indexed | 2024-03-11T15:42:07Z |
| format | Article |
| id | doaj.art-55e4f249020d4887a0a85ff88159d938 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-03-11T15:42:07Z |
| publishDate | 2023-10-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-55e4f249020d4887a0a85ff88159d9382023-10-26T11:20:01ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2023-10-011710131710.7860/JCDR/2023/66902.18557Evaluation of Protein Adsorption and Osseointegration Potential of Polyetheretherketone versus Titanium Dental Implants: A Systematic ReviewSeema Patil0Paresh Gandhi1Aditi Kanitkar2Rupali Patil3Bhagyashree Kalsekar4Assistant Professor, Department of Prosthodontics and Crown and Bridge, BVDU, DCH, Pune, Maharashtra, India.Professor, Department of Prosthodontics and Crown and Bridge, BVDU, DCH, Pune, Maharashtra, India.Assistant Professor, Department of Prosthodontics and Crown and Bridge, BVDU, DCH, Pune, Maharashtra, India.Associate Professor, Department of Prosthodontics and Crown and Bridge, BVDU, DCH, Pune, Maharashtra, India.Assistant Professor, Department of Prosthodontics and Crown and Bridge, BVDU, DCH, Pune, Maharashtra, India.Introduction: The success of implant therapy depends on a number of parameters, including bone volume implant shape, surface topography, the patient’s overall health, and local factors. Despite the fact that polyetheretherketone (PEEK) implants have undergone a lot of alterations, only a small number of studies have examined the bioactivity and osseointegration of PEEK implants with titanium. Aim: To summarise and evaluate protein adsorption and osseointegration capacity of PEEK and titanium dental implants. Materials and Methods: Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines were used and PROSPERO (CRD42023415494) registration was done. Electronic databases were searched for studies assessing the outcome in terms of protein adsorption and osseointegration capacity of PEEK and titanium dental implants. Quality assessment of included studies was evaluated using the Newcastle-Ottawa Scale (NOS). Results: Depending on inclusion and exclusion criteria, seven studies fulfilled the eligibility criteria and were included in qualitative synthesis. Risk of bias assessment revealed that all the included studies were largely comparable in methodological quality. All the included studies had moderate to low-risk of bias with all the respective domains. All the included studies revealed that PEEK with optimal surface roughness might hold great potential for protein adsorption and osseointegration capacity. Conclusion: Within the limitations of the study, it was found that compared to titanium, PEEK is less osseoconductive and bioactive. PEEK is therefore unsuitable for use as a dental implant in its unmodified form. Implantitis and implant failure occurs from improper osseoconductivity and bioactivity of dental implants.https://www.jcdr.net/articles/PDF/18557/66902_CE[Ra1]_F(SS)_PF1(KB_OM)_PFA(KB_KM)_PN(KM).pdfbioactivenewcastle-ottawa scaleosseoconductivity |
| spellingShingle | Seema Patil Paresh Gandhi Aditi Kanitkar Rupali Patil Bhagyashree Kalsekar Evaluation of Protein Adsorption and Osseointegration Potential of Polyetheretherketone versus Titanium Dental Implants: A Systematic Review Journal of Clinical and Diagnostic Research bioactive newcastle-ottawa scale osseoconductivity |
| title | Evaluation of Protein Adsorption and Osseointegration Potential of Polyetheretherketone versus Titanium Dental Implants: A Systematic Review |
| title_full | Evaluation of Protein Adsorption and Osseointegration Potential of Polyetheretherketone versus Titanium Dental Implants: A Systematic Review |
| title_fullStr | Evaluation of Protein Adsorption and Osseointegration Potential of Polyetheretherketone versus Titanium Dental Implants: A Systematic Review |
| title_full_unstemmed | Evaluation of Protein Adsorption and Osseointegration Potential of Polyetheretherketone versus Titanium Dental Implants: A Systematic Review |
| title_short | Evaluation of Protein Adsorption and Osseointegration Potential of Polyetheretherketone versus Titanium Dental Implants: A Systematic Review |
| title_sort | evaluation of protein adsorption and osseointegration potential of polyetheretherketone versus titanium dental implants a systematic review |
| topic | bioactive newcastle-ottawa scale osseoconductivity |
| url | https://www.jcdr.net/articles/PDF/18557/66902_CE[Ra1]_F(SS)_PF1(KB_OM)_PFA(KB_KM)_PN(KM).pdf |
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