Transient Receptor Potential Mucolipin-1 Channels in Glioblastoma: Role in Patient’s Survival
A link between mucolipin channels and tumors has been recently suggested. Herein, we aim to investigate the transient receptor potential mucolipin (TRPML)-1 relevance in glioblastoma. The expression of this channel was evaluated via qRT-PCR and immunohistochemistry in biopsies from 66 glioblastoma p...
Main Authors: | Maria Beatrice Morelli, Consuelo Amantini, Daniele Tomassoni, Massimo Nabissi, Antonella Arcella, Giorgio Santoni |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-04-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/11/4/525 |
Similar Items
-
Coexpression of TRPML1 and TRPML2 Mucolipin Channels Affects the Survival of Glioblastoma Patients
by: Giorgio Santoni, et al.
Published: (2022-07-01) -
Functional In Vitro Assessment of VEGFA/NOTCH2 Signaling Pathway and pRB Proteasomal Degradation and the Clinical Relevance of Mucolipin TRPML2 Overexpression in Glioblastoma Patients
by: Giorgio Santoni, et al.
Published: (2022-01-01) -
Knock-Down of Mucolipin 1 Channel Promotes Tumor Progression and Invasion in Human Glioblastoma Cell Lines
by: Giorgio Santoni, et al.
Published: (2021-04-01) -
Involvement of the TRPML Mucolipin Channels in Viral Infections and Anti-viral Innate Immune Responses
by: Giorgio Santoni, et al.
Published: (2020-04-01) -
TRPML2 Mucolipin Channels Drive the Response of Glioma Stem Cells to Temozolomide and Affect the Overall Survival in Glioblastoma Patients
by: Maria Beatrice Morelli, et al.
Published: (2022-12-01)