CXCR2 Blockade Mitigates Neural Cell Injury Following Preclinical Chorioamnionitis

CXCR2 Blockade Mitigates Neural Cell Injury Following Preclinical Chorioamnionitis

Minimizing central nervous system (CNS) injury from preterm birth depends upon identification of the critical pathways that underlie essential neurodevelopmental and CNS pathophysiology. While chorioamnionitis (CHORIO), is a leading cause of preterm birth, the precise mechanism linking prenatal brai...

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Bibliographic Details
Main Authors: Tracylyn R. Yellowhair, Jessie C. Newville, Shahani Noor, Jessie R. Maxwell, Erin D. Milligan, Shenandoah Robinson, Lauren L. Jantzie
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Physiology
Subjects:
preterm
chemokine
CXCL1
diffusion tensor imaging
neutrophil
white matter
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00324/full

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