Asymptomatic Barrett’s Oesophagus-Complicated Gastroesophageal Reflux Disease at Ineffective Antisecretory Therapy
Aim. A clinical description of gastroesophageal reflux disease (GERD) complicated by Barrett’s oesophagus (BO) at inadequate antisecretory therapy and the assessment of functional tests in control of conservative treatment.Key points. A 63-yo patient with no complaints in a proton pump inhibitor (PP...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2021-06-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/558 |
| _version_ | 1797245188575330304 |
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| author | E. V. Barkalova S. S. Pirogov D. N. Andreev M. A. Ovsepyan I. V. Maev A. D. Kaprin |
| author_facet | E. V. Barkalova S. S. Pirogov D. N. Andreev M. A. Ovsepyan I. V. Maev A. D. Kaprin |
| author_sort | E. V. Barkalova |
| collection | DOAJ |
| description | Aim. A clinical description of gastroesophageal reflux disease (GERD) complicated by Barrett’s oesophagus (BO) at inadequate antisecretory therapy and the assessment of functional tests in control of conservative treatment.Key points. A 63-yo patient with no complaints in a proton pump inhibitor (PPI) therapy was admitted for a follow-up examination for BO-complicated GERD using oesophagogastroduodenoscopy (OGDS) with biopsy, high-resolution oesophageal manometry and 24-h pH-impedance. Endoscopy revealed signs of BO (long segment C1M3), erosive reflux oesophagitis (grade B in Los Angeles classification). Non-contractile oesophagus in manometry. Antisecretory therapy was stated ineffective and subject to correction in 24-h pH-impedance.Conclusion. Asymptomatic BO-complicated GERD patients comprise a special cohort. The main challenge to prevent progression into oesophageal adenocarcinoma is an adequate personalised patient management leveraging the modern diagnostic techniques, control of antisecretory treatment and its correction a situ. |
| first_indexed | 2024-03-08T09:20:53Z |
| format | Article |
| id | doaj.art-55eb8191b7d04e3c8fb243aefc7496cb |
| institution | Directory Open Access Journal |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| last_indexed | 2024-04-24T19:22:56Z |
| publishDate | 2021-06-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj.art-55eb8191b7d04e3c8fb243aefc7496cb2024-03-25T16:53:09ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732021-06-01312465310.22416/1382-4376-2021-31-2-46-53418Asymptomatic Barrett’s Oesophagus-Complicated Gastroesophageal Reflux Disease at Ineffective Antisecretory TherapyE. V. Barkalova0S. S. Pirogov1D. N. Andreev2M. A. Ovsepyan3I. V. Maev4A. D. Kaprin5Yevdokimov Moscow State University of Medicine and DentistryNational Medical Research Radiology CentreYevdokimov Moscow State University of Medicine and DentistryYevdokimov Moscow State University of Medicine and DentistryYevdokimov Moscow State University of Medicine and DentistryNational Medical Research Radiology CentreAim. A clinical description of gastroesophageal reflux disease (GERD) complicated by Barrett’s oesophagus (BO) at inadequate antisecretory therapy and the assessment of functional tests in control of conservative treatment.Key points. A 63-yo patient with no complaints in a proton pump inhibitor (PPI) therapy was admitted for a follow-up examination for BO-complicated GERD using oesophagogastroduodenoscopy (OGDS) with biopsy, high-resolution oesophageal manometry and 24-h pH-impedance. Endoscopy revealed signs of BO (long segment C1M3), erosive reflux oesophagitis (grade B in Los Angeles classification). Non-contractile oesophagus in manometry. Antisecretory therapy was stated ineffective and subject to correction in 24-h pH-impedance.Conclusion. Asymptomatic BO-complicated GERD patients comprise a special cohort. The main challenge to prevent progression into oesophageal adenocarcinoma is an adequate personalised patient management leveraging the modern diagnostic techniques, control of antisecretory treatment and its correction a situ.https://www.gastro-j.ru/jour/article/view/558barrett’s oesophagusoesophagogastroscopyhigh-resolution oesophageal manometry24-h ph-impedance |
| spellingShingle | E. V. Barkalova S. S. Pirogov D. N. Andreev M. A. Ovsepyan I. V. Maev A. D. Kaprin Asymptomatic Barrett’s Oesophagus-Complicated Gastroesophageal Reflux Disease at Ineffective Antisecretory Therapy Российский журнал гастроэнтерологии, гепатологии, колопроктологии barrett’s oesophagus oesophagogastroscopy high-resolution oesophageal manometry 24-h ph-impedance |
| title | Asymptomatic Barrett’s Oesophagus-Complicated Gastroesophageal Reflux Disease at Ineffective Antisecretory Therapy |
| title_full | Asymptomatic Barrett’s Oesophagus-Complicated Gastroesophageal Reflux Disease at Ineffective Antisecretory Therapy |
| title_fullStr | Asymptomatic Barrett’s Oesophagus-Complicated Gastroesophageal Reflux Disease at Ineffective Antisecretory Therapy |
| title_full_unstemmed | Asymptomatic Barrett’s Oesophagus-Complicated Gastroesophageal Reflux Disease at Ineffective Antisecretory Therapy |
| title_short | Asymptomatic Barrett’s Oesophagus-Complicated Gastroesophageal Reflux Disease at Ineffective Antisecretory Therapy |
| title_sort | asymptomatic barrett s oesophagus complicated gastroesophageal reflux disease at ineffective antisecretory therapy |
| topic | barrett’s oesophagus oesophagogastroscopy high-resolution oesophageal manometry 24-h ph-impedance |
| url | https://www.gastro-j.ru/jour/article/view/558 |
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