Synthesis of ∆3-2-Hydroxybakuchiol Analogues and Their Growth Inhibitory Activity against Rat UMR106 Cells

Synthesis of ∆3-2-Hydroxybakuchiol Analogues and Their Growth Inhibitory Activity against Rat UMR106 Cells

A series of ∆3-2-hydroxybakuchiol analogues have been synthesized and tested for their growth inhibitory activity against rat UMR106 cells by using the MTT method. Some of them exhibit enhanced activities compared with the natural product, and the preliminary SAR profile shows that the chain tail on...

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Bibliographic Details
Main Authors: Qun Zhao, Qianqian Xu, Guangsheng Shan, Chao Dong, Hong Zhang, Xinsheng Lei
Format: Article
Language:English
Published: MDPI AG 2014-02-01
Series:Molecules
Subjects:
bakuchiol
natural product analogues
cytotoxic activity
Online Access:http://www.mdpi.com/1420-3049/19/2/2213

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